About: Cardiac manifestations of COVID-19 in Shenzhen, China

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Cardiac manifestations of COVID-19 in Shenzhen, China
Creator	Feng, Cheng Qu, Jiu-Xin Wang, Yao Feng, · Dong, Chang-Feng Feng, Wen-Xia Luo, Yong-Fang Wu, Wei-Bo Zeng, Jia-Hui Zhou, Dan Zeng, J.-H
Source	Medline; PMC
abstract	PURPOSE: The coronavirus disease 2019 (COVID-19) outbreak has become a global public health concern; however, relatively few detailed reports of related cardiac injury are available. The aims of this study were to compare the clinical and echocardiographic characteristics of inpatients in the intensive-care unit (ICU) and non-ICU patients. METHODS: We recruited 416 patients diagnosed with COVID-19 and divided them into two groups: ICU (n = 35) and non-ICU (n = 381). Medical histories, laboratory findings, and echocardiography data were compared. RESULTS: The levels of myocardial injury markers in ICU vs non-ICU patients were as follows: troponin I (0.029 ng/mL [0.007–0.063] vs 0.006 ng/mL [0.006–0.006]) and myoglobin (65.45 μg/L [39.77–130.57] vs 37.00 μg/L [26.40–53.54]). Echocardiographic findings included ventricular wall thickening (12 [39%] vs 1 [4%]), pulmonary hypertension (9 [29%] vs 0 [0%]), and reduced left-ventricular ejection fraction (5 [16%] vs 0 [0%]). Overall, 10% of the ICU patients presented with right heart enlargement, thickened right-ventricular wall, decreased right heart function, and pericardial effusion. Cardiac complications were more common in ICU patients, including acute cardiac injury (21 [60%] vs 13 [3%]) (including 2 cases of fulminant myocarditis), atrial or ventricular tachyarrhythmia (3 [9%] vs 3 [1%]), and acute heart failure (5 [14%] vs 0 [0%]). CONCLUSION: Myocardial injury marker elevation, ventricular wall thickening, pulmonary artery hypertension, and cardiac complications including acute myocardial injury, arrhythmia, and acute heart failure are more common in ICU patients with COVID-19. Cardiac injury in COVID-19 patients may be related more to the systemic response after infection rather than direct damage by coronavirus.
has issue date	2020-07-28(xsd:dateTime)
bibo:doi	10.1007/s15010-020-01473-w
bibo:pmid	32725595
has license	no-cc
sha1sum (hex)	32504110f93120a08331545fa98f56f6a4bc60aa
schema:url	https://doi.org/10.1007/s15010-020-01473-w
resource representing a document's title	Cardiac manifestations of COVID-19 in Shenzhen, China
has PubMed Central identifier	PMC7386384
has PubMed identifier	32725595
schema:publication	Infection
resource representing a document's body	covid:32504110f93120a08331545fa98f56f6a4bc60aa#body_text
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