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About:
Renin-Angiotensin System Inhibition in Cardiovascular Patients at the Time of COVID19: Much Ado for Nothing? A Statement of Activity from the Directors of the Board and the Scientific Directors of the Italian Society of Hypertension
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
covidontheweb.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
New Facet based on Instances of this Class
Attributes
Values
type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Renin-Angiotensin System Inhibition in Cardiovascular Patients at the Time of COVID19: Much Ado for Nothing? A Statement of Activity from the Directors of the Board and the Scientific Directors of the Italian Society of Hypertension
Creator
Arrigo, ·
Borghi, Claudio
Cicero, F
Ferri, Claudio
Grassi, Guido
Iaccarino, Guido
Leonardo, ·
Massimo Volpe, ·
Minuz, Pietro
Muiesan, Maria
Mulatero, Paolo
Mulè, Giuseppe
Pucci, Giacomo
Salvetti, Massimo
Savoia, Carmine
Sechi, Alberto
Source
Medline; PMC
abstract
Cardiovascular diseases, in particular hypertension, as well as the cardiovascular treatment with Renin–Angiotensin System inhibitors such as Angiotensin Converting Enzyme (ACE) inhibitors and Angiotensin Receptor Blockers (ARBs), are claimed once again as mechanisms of Severe Acute Respiratory Syndrome (SARS) during the COVID-19 outbreak due to Cov-2 epidemics. In vitro studies are available to support the eventual role of ACE inhibitors and ARBs in both the promotion and antagonism of the disease. The available literature, indeed, presents contrasting results, all concentrated in experimental models. Evidence in humans is lacking that those mechanisms are actually occurring in the present COVID-19 outbreak. Here we present the reasoned statement of the Italian Society of Hypertension to maintain ongoing antihypertensive treatments. Furthermore, the Italian Society of Hypertension presents its own initiative to investigate the issue using an online questionnaire to collect relevant data in human disease.
has issue date
2020-04-07
(
xsd:dateTime
)
bibo:doi
10.1007/s40292-020-00380-3
bibo:pmid
32266708
has license
no-cc
sha1sum (hex)
31f3c18d51946fd9e1afcc4d24cb5454d17359ae
schema:url
https://doi.org/10.1007/s40292-020-00380-3
resource representing a document's title
Renin-Angiotensin System Inhibition in Cardiovascular Patients at the Time of COVID19: Much Ado for Nothing? A Statement of Activity from the Directors of the Board and the Scientific Directors of the Italian Society of Hypertension
has PubMed Central identifier
PMC7138256
has PubMed identifier
32266708
schema:publication
High Blood Press Cardiovasc Prev
resource representing a document's body
covid:31f3c18d51946fd9e1afcc4d24cb5454d17359ae#body_text
is
schema:about
of
named entity 'Board'
named entity 'Patients'
named entity 'Statement'
named entity 'Inhibition'
named entity 'Nothing'
named entity 'Cardiovascular diseases'
named entity 'CLINICAL GUIDELINES'
named entity 'Hypertension'
named entity 'Cardiovascular'
named entity 'kidney'
named entity 'ARBs'
named entity 'hypertensive'
named entity 'infection'
named entity 'cardiovascular disease'
named entity 'infection'
named entity 'ACE2'
named entity 'ACE inhibitors'
named entity 'COVID-19 disease'
named entity 'ARBs'
named entity 'membrane-bound'
named entity 'angiotensin-converting enzyme'
named entity 'ACE2'
named entity 'ACE'
named entity 'ACE2'
named entity 'spread of the disease'
named entity 'COVID'
named entity 'COVID-19'
named entity 'ACE'
named entity 'receptor'
named entity 'ACE'
named entity 'upregulation'
named entity 'SARS-CoV-2'
named entity 'ACE inhibitors'
named entity 'animal studies'
named entity 'carboxypeptidase'
named entity 'angiotensin II receptor type 1'
named entity 'antihypertensive treatment'
named entity 'ACE inhibitors'
named entity 'ACE2'
named entity 'lung'
named entity 'Italian'
named entity 'ARBs'
named entity 'Angiotensin II'
named entity 'Coronavirus'
named entity 'COVID'
named entity 'clinicaltrials.gov'
named entity 'angiotensin II'
named entity 'ARBs'
named entity 'upregulation'
named entity 'ARBs'
named entity 'cardiovascular disease'
named entity 'spike protein'
named entity 'human lung'
named entity 'SARS'
named entity 'RAS'
named entity 'ACE Inhibitors'
named entity 'hypertension'
named entity 'ACE2'
named entity 'sepsis'
named entity 'ACE2'
named entity 'upregulation'
named entity 'epidemic'
named entity 'word of mouth'
named entity 'enzyme'
named entity 'ACE inhibitors'
named entity 'attenuation'
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