About: Human Coronaviruses: A Review of Virus

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Human Coronaviruses: A Review of Virus–Host Interactions
Creator	Liu, Ding Tam, James Lim, Yvonne Ng, Yan
source	Medline; PMC
abstract	Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) have thrust HCoVs into spotlight of the research community due to their high pathogenicity in humans. The study of HCoV-host interactions has contributed extensively to our understanding of HCoV pathogenesis. In this review, we discuss some of the recent findings of host cell factors that might be exploited by HCoVs to facilitate their own replication cycle. We also discuss various cellular processes, such as apoptosis, innate immunity, ER stress response, mitogen-activated protein kinase (MAPK) pathway and nuclear factor kappa B (NF-κB) pathway that may be modulated by HCoVs.
has issue date	2016-07-25(xsd:dateTime)
bibo:doi	10.3390/diseases4030026
bibo:pmid	28933406
has license	cc-by
sha1sum (hex)	30abdf7a423427b001aee5d319abecfb5ad1671b
schema:url	https://doi.org/10.3390/diseases4030026
resource representing a document's title	Human Coronaviruses: A Review of Virus–Host Interactions
has PubMed Central identifier	PMC5456285
has PubMed identifier	28933406
schema:publication	Diseases
resource representing a document's body	covid:30abdf7a423427b001aee5d319abecfb5ad1671b#body_text
is schema:about of	named entity 'INTERACTIONS' named entity 'extensively' named entity 'MAPK' named entity 'onset' named entity 'interactions' named entity 'humans' named entity 'cell' named entity 'ER stress' named entity 'HOST' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'HUMANS' named entity 'FINDINGS' named entity 'INNATE IMMUNITY' named entity 'IN THE PAST' named entity 'PATHOGENESIS' named entity 'CORONAVIRUSES' named entity 'OUR' named entity 'KNOWN' named entity 'MODULATED' named entity 'STUDY' named entity 'MITOGEN-ACTIVATED PROTEIN KINASE' named entity 'PATHWAY' named entity 'BAB' named entity 'THRUST' named entity 'THEIR' named entity 'PATHOGENICITY' named entity 'HIGH' named entity 'HOST CELL' named entity 'OUTCOMES' named entity 'INTERACTIONS' named entity 'RESEARCH COMMUNITY' named entity 'APOPTOSIS' named entity 'RECENT' named entity 'DUE TO' named entity 'HUMAN' named entity 'VARIOUS' named entity 'ER STRESS RESPONSE' named entity 'CORONAVIRUSES' named entity 'RESPIRATORY PATHOGENS' named entity 'REPLICATION CYCLE' named entity 'CELLULAR PROCESSES' named entity 'MIGHT BE' named entity 'HOST' named entity 'REVIEW OF' named entity 'VIRUS' named entity 'HUMAN' named entity 'DISCUSS' named entity 'HAVE' named entity 'REVIEW' named entity 'ONSET OF' named entity 'RANGE' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS' named entity 'RESPIRATORY' named entity 'NUCLEAR FACTOR KAPPA B' named entity 'UNDERSTANDING' named entity 'ASSOCIATED WITH' named entity 'YEARS' named entity 'Human' named entity 'apoptosis' named entity 'host' named entity 'coronaviruses' named entity 'SARS-CoV' named entity 'pathogenesis' named entity 'ER stress' named entity 'pathogenicity' named entity 'Human Coronaviruses' named entity 'nucleocapsid' named entity 'NF-κB' named entity 'ATF4' named entity 'virus' named entity 'type I IFN' named entity 'CCL5' named entity 'enveloped virus' named entity 'SARS-CoV' named entity 'protein' named entity 'SARS-CoV' named entity 'RNA pseudoknot' named entity 'aminopeptidase'

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