About: Edible bird's nest extract inhibits influenza virus infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Edible bird's nest extract inhibits influenza virus infection
Creator	Kato, Koichi Suzuki, Takashi Bukawa, Wakoto Guo, Chao-Tan Miyamoto, Daisei Suzuki, Yasuo Takahashi, Noriko Takahashi, Tadanobu Yagi, Hirokazu Jwa Hidari, I.-P
Source	Elsevier; Medline; PMC
abstract	Abstract Edible bird's nest (EBN) is the nest of the swift that is made from its saliva. Although EBN has been widely used for enhancing immunocompetence, its antiviral efficacy has not been studied in detail. We found that EBN extract could strongly inhibit infection with influenza viruses in a host range-independent manner when it was hydrolyzed with Pancreatin F. Western blotting assay showed that the EBN extract bound to influenza virus. Furthermore, EBN extract could neutralize the infection of MDCK cells with influenza viruses and inhibit hemagglutination of influenza viruses to erythrocytes, but it could not inhibit the activity of influenza virus sialidase. Fluorometric HPLC indicated that the major molecular species of sialic acid in EBN is N-acetylneuraminic acid. The results suggest that EBN is a safe and valid natural source for the prevention of influenza viruses.
has issue date	2006-07-31(xsd:dateTime)
bibo:doi	10.1016/j.antiviral.2006.02.005
bibo:pmid	16581142
has license	els-covid
sha1sum (hex)	2fd2b463d072709f813243e7ff45e810022d4048
schema:url	https://doi.org/10.1016/j.antiviral.2006.02.005
resource representing a document's title	Edible bird's nest extract inhibits influenza virus infection
has PubMed Central identifier	PMC7114130
has PubMed identifier	16581142
schema:publication	Antiviral Research
resource representing a document's body	covid:2fd2b463d072709f813243e7ff45e810022d4048#body_text
is schema:about of	named entity 'viruses' named entity 'hydrolyzed' named entity 'inhibit' named entity 'nest' named entity 'nest' named entity 'Edible' named entity 'extract' named entity 'INFLUENZA VIRUSES' named entity 'IMMUNOCOMPETENCE' named entity 'MOLECULAR' named entity 'BIRD' named entity 'N-ACETYLNEURAMINIC ACID' named entity 'NEST' named entity 'SAFE' named entity 'SWIFT' named entity 'INFLUENZA VIRUS' named entity 'SIALIC ACID' named entity 'HPLC' named entity 'ASSAY' named entity 'VALID' named entity 'INDEPENDENT' named entity 'VIRUS INFECTION' named entity 'PREVENTION OF' named entity 'EDIBLE' named entity 'BIRD' named entity 'EXTRACT' named entity 'EXTRACT' named entity 'EBN' named entity 'HOST RANGE' named entity 'USED' named entity 'SUGGEST' named entity 'SPECIES' named entity 'ACTIVITY' named entity 'FOUND' named entity 'NEST' named entity 'MAJOR' named entity 'EFFICACY' named entity 'BUT' named entity 'MDCK CELLS' named entity 'IS A' named entity 'HEMAGGLUTINATION' named entity 'INFLUENZA VIRUS' named entity 'ERYTHROCYTES' named entity 'INDICATED' named entity 'ANTIVIRAL' named entity 'BOUND' named entity 'WESTERN BLOTTING' named entity '27S' named entity 'NATURAL SOURCE' named entity 'INFECTION' named entity 'RESULTS' named entity 'ITS' named entity 'PANCREATIN' named entity '27S' named entity 'SALIVA' named entity 'ENHANCING' named entity 'EDIBLE' named entity 'SIALIDASE' covid:arg/2fd2b463d072709f813243e7ff45e810022d4048 named entity 'infection' named entity 'viruses' named entity 'EBN' named entity 'host' named entity 'bird' named entity 'influenza' named entity 'hydrolyzed' named entity 'MDCK' named entity 'sialidase' named entity 'influenza virus' named entity 'assay' named entity 'host range' named entity 'molecular species'

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