About: Awake prone positioning for COVID-19 hypoxemic respiratory failure: A rapid review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Awake prone positioning for COVID-19 hypoxemic respiratory failure: A rapid review
Creator	Ca, Fiest, Kirsten Solverson, Kevin Weatherald, Jason Ca, Dan Ca, Kevin Fiest Phd, Kirsten Kuljit, Ken Loroff, Nicole Parhar, S Parhar@albertahealthservices, Ken Zuege, Danny
Source	Elsevier; PMC
abstract	BACKGROUND: Infection with SARS-CoV-2 can result in Coronavirus Disease–19 (COVID-19) [1, 2]. While the majority of patients are asymptomatic or have mild disease [3], approximately 14% develop more severe disease including hypoxemic respiratory failure and/or Acute Respiratory Distress Syndrome (ARDS) [3]. Prone positioning is a life-saving intervention for mechanically ventilated patients with moderate-severe ARDS [4]. Based on this, the World Health Organization (WHO) guidelines recommend these patients be considered for a trial of prone positioning [5]. Recently the use of prone positioning in awake non-intubated COVID-19 patients has been recommended by several notable organizations with the goal of preventing intubation and potentially improving patient-oriented outcomes [6, 7]. In contrast to prone positioning for intubated mechanically ventilated patients with ARDS, there have been no randomized control trials examining the role of awake prone positioning for non-intubated patients with hypoxemic respiratory failure. To further explore this question we used rapid review methodology (Tricco et al., 2015 [8]) to quickly identify and synthesize studies examining the effect of awake prone positioning on patients with hypoxemic respiratory failure (including those with ARDS and/or COVID-19). METHODS: We have elected to use “rapid review” methodology rather than “systematic review” methodology primarily due to the speed and efficiency through which we are able to conduct this review, as previously described [8]. In the absence of an EQUATOR guidance document, we used PRISMA guidelines where applicable [9]. Studies were included if they met the following criteria 1) population – non-intubated patients with hypoxemic respiratory failure, 2) intervention – prone positioning, 3) comparator – usual management, 4) outcomes – intubation, survival, change in respiratory parameters, adverse events, 5) setting – hospitalized patients 6) study design – observational or randomized control trial. Studies were not limited to ARDS or COVID-19 patients. The search strategy was developed by a critical care physician (KP), a critical care epidemiologist (KF) and a medical librarian (NL) (See search details in Online Supplement). Briefly, the search strategy involved combinations of keywords and subject headings relating to the concepts of, 1) SARS-Cov-2 or COVID-19 or coronavirus, 2) awake prone positioning, and 3) hypoxemic respiratory failure, including but not limited to ARDS and other potentially relevant conditions. The search was conducted on May 19, 2020 and was updated on August 7, 2020 with no restrictions on publication language or date. Databases and grey literature sources searched included: MEDLINE (Ovid), PubMed, Trip PRO, Cochrane Library, LitCOVID, WHO COVID-19 Research Database, Centre for Evidence-Based Medicine (CEBM), National Institute for Health and Care Excellence (NICE), medRxiv, BMJ Best Practice, Cambridge Coronavirus Free Access Collection, and Google Scholar. Titles and abstracts were reviewed independently and in duplicate (KP and JW) for selection for full text review. Disagreements were resolved through discussion or with a third reviewer (KS). Full text review and data abstraction was conducted independently and in duplicate (KP, KS, JW). Data abstracted included study characteristics, participant demographics, and outcomes.
has issue date	2020-08-27(xsd:dateTime)
bibo:doi	10.1016/j.jcrc.2020.08.018
has license	no-cc
sha1sum (hex)	2d195dfa39a57a855b4e61253191f0a1c337a9a7
schema:url	https://doi.org/10.1016/j.jcrc.2020.08.018
resource representing a document's title	Awake prone positioning for COVID-19 hypoxemic respiratory failure: A rapid review
has PubMed Central identifier	PMC7450241
schema:publication	J Crit Care
resource representing a document's body	covid:2d195dfa39a57a855b4e61253191f0a1c337a9a7#body_text
is schema:about of	named entity 'BASED' covid:arg/2d195dfa39a57a855b4e61253191f0a1c337a9a7 named entity 'ARDS' named entity 'mechanically ventilated' named entity 'ARDS' named entity 'COVID' named entity 'Hypoxemic' named entity 'COVID' named entity 'respiratory failure' named entity 'hospital ward' named entity 'intubation' named entity 'supine position' named entity 'ARDS' named entity 'clinician' named entity 'case studies' named entity 'prone position' named entity 'intubated' named entity 'patient outcomes' named entity 'invasive mechanical ventilation' named entity 'decision making' named entity 'ARDS' named entity 'adverse events' named entity 'cohort studies' named entity 'clinical outcomes' named entity 'adverse events' named entity 'emergency department' named entity 'intubated' named entity 'follow-up' named entity 'sedation' named entity 'ICU' named entity 'ICU' named entity 'lung' named entity 'COVID-19' named entity 'case reports' named entity 'prone position' named entity 'meta-analyses' named entity 'randomized control trials' named entity 'ARDS' named entity 'sample sizes' named entity 'Adverse events' named entity 'prone position' named entity 'ventilator' named entity 'intubated' named entity 'respiratory failure' named entity 'paralysis' named entity 'lung' named entity 'social media' named entity 'control group' named entity 'self-inflicted' named entity 'COVID-19' named entity 'lung' named entity 'hypoxemic' named entity 'case reports' named entity 'case reports' named entity 'ventilator' named entity 'randomized controlled trials' named entity 'hypoxemia' named entity 'COVID-19' named entity 'ICU' named entity 'sternal' named entity 'hypoxemia' named entity 'nosebleeds' named entity 'hypoxemic' named entity 'hypoxemic' named entity 'Infection' named entity 'asymptomatic' named entity 'SARS-CoV-2' named entity 'respiratory failure' named entity 'APPROXIMATELY' named entity 'INFECTION' named entity 'HAVE' named entity 'SEVERE DISEASE'

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