About: A cluster of adenovirus type B55 infection in a neurosurgical inpatient department of a general hospital in Guangdong, China

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About: A cluster of adenovirus type B55 infection in a neurosurgical inpatient department of a general hospital in Guangdong, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A cluster of adenovirus type B55 infection in a neurosurgical inpatient department of a general hospital in Guangdong, China
Creator	Ke, Changwen Kang, Min Liang, Lijun Song, Yingchao Wu, Jie Zou, Lirong Zhang, Xin Lu, Jing Su, Juan Yi, Lina Ni, Hanzhong
Source	Medline; PMC
abstract	BACKGROUND: Human adenovirus type 55 is a re‐emerging human respiratory pathogen that is associated with several respiratory infections outbreaks in military and school populations. In this study, we describe the first HAdV55‐associated hospital outbreak documented in Guangdong, China. METHODS: Active surveillance was conducted in the involved neurosurgical inpatient department. All staff and patients in the involved neurosurgical department were surveyed for any symptoms of fever (≥38°C) and enlarged tonsils during the outbreak period. Throat swabs and demographic information were collected for all cases. For each specimen, assays for common respiratory viruses were performed using one‐step reverse transcription‐polymerase chain reaction. HAdV‐positive samples were inoculated onto Hep‐2 cells for isolation. Hexon genes, fiber genes, penton genes, and whole genomes were sequenced. A phylogenetic tree was constructed. RESULTS AND CONCLUSIONS: Forty‐three cases, including 24 laboratory‐confirmed cases and 19 possible cases, were identified. Nurses had the highest attack rate of infection, with a rate of 36.4%. The attack rate for doctors and inpatients was 20.0% and 16.7%, respectively. HAdV55 was the sole pathogen identified during this outbreak. The hexon, fiber, and penton genes from seven isolated HAdV55 stains were sequenced. All these genes showed 100% homology and fell into the HAdV55 [P14H11F14] cluster, indicating that HAdV55 was the single viral strain for the outbreak. While not conclusive, the epidemic investigation revealed that the outbreak was introduced by nurses from sources outside the hospital. It was likely that a transmission from staff to inpatients had occurred.
has issue date	2017-06-26(xsd:dateTime)
bibo:doi	10.1111/irv.12457
bibo:pmid	28488368
has license	cc-by
sha1sum (hex)	2ce201c2ba233a562ee605a9aa12d2719cfa2beb
schema:url	https://doi.org/10.1111/irv.12457
resource representing a document's title	A cluster of adenovirus type B55 infection in a neurosurgical inpatient department of a general hospital in Guangdong, China
has PubMed Central identifier	PMC5485872
has PubMed identifier	28488368
schema:publication	Influenza Other Respir Viruses
resource representing a document's body	covid:2ce201c2ba233a562ee605a9aa12d2719cfa2beb#body_text
is schema:about of	named entity 'B55' named entity 'HUMAN ADENOVIRUS' named entity 'HUMAN' named entity 'BACKGROUND' named entity 'DEPARTMENT' named entity 'OUTBREAK' named entity 'CHINA' named entity 'IS A' named entity 'HUMAN ADENOVIRUS' named entity 'OUTBREAKS' named entity 'RESPIRATORY INFECTIONS' named entity 'HUMAN' named entity 'SCHOOL' named entity 'RESPIRATORY' named entity 'RESPIRATORY' named entity 'ASSOCIATED WITH' named entity 'STUDY' named entity 'POPULATIONS' named entity 'GENERAL HOSPITAL' named entity 'ADENOVIRUS TYPE' named entity 'CLUSTER' named entity 'INFECTION' named entity 'IS A' named entity 'INPATIENT' named entity 'PATHOGEN' named entity 'CHINA' named entity 'PATHOGEN' named entity 'DESCRIBE' named entity 'BACKGROUND' named entity 'ADENOVIRUS TYPE' named entity 'MILITARY' named entity 'ASSOCIATED' named entity 'HOSPITAL' named entity 'DOCUMENTED' covid:arg/2ce201c2ba233a562ee605a9aa12d2719cfa2beb named entity 'Guangdong' named entity 'pathogen' named entity 'infection' named entity 'general hospital' named entity 'neurosurgical' named entity 'acupuncturist' named entity 'pneumonia' named entity 'Center for Disease Control and Prevention' named entity 'hexon' named entity 'nosocomial infection' named entity 'expectoration' named entity 'infection' named entity 'nucleotide substitution' named entity 'gamma distribution' named entity 'medical workers' named entity 'gene' named entity 'China' named entity 'hexon' named entity 'enlarged tonsils' named entity 'sore throat' named entity 'SPSS Inc.' named entity 'mechanical ventilation' named entity 'adenovirus' named entity 'virus' named entity 'primers' named entity 'genotypes' named entity 'symptom' named entity 'respiratory symptoms' named entity 'June 11' named entity 'gene' named entity 'respiratory infections' named entity 'Chicago' named entity 'pathogen' named entity 'pneumonia' named entity 'Guangdong' named entity 'medical records'

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