About: Solid organ transplantation following allogeneic haematopoietic cell transplantation: experience from a referral organ transplantation center and systematic review of literature

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About: Solid organ transplantation following allogeneic haematopoietic cell transplantation: experience from a referral organ transplantation center and systematic review of literature Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Solid organ transplantation following allogeneic haematopoietic cell transplantation: experience from a referral organ transplantation center and systematic review of literature
Creator	Aljurf, Mahmoud Brockmann, Jens Broering, Dieter Hashmi, Shahrukh Rasheed, Walid Shagrani, Mohamed Alburaiki, A Chaudhri, • Imran, • Jehad, • Nizami, Y Raza, M Syed, • Tariq, •
Source	PMC
abstract	Solid organ transplantation (SOT) following haematopoietic cell transplantation (HCT) is a rare event. Uncertainty exists whether such recipients are at higher risk of relapse of underlying haematological disease or at increased risk of developing infectious or immunological complications and malignancies following SOT. The experience at our referral organ transplantation center and the present literature of SOT (n = 198) in recipients following previous HCT was systematically reviewed. Outcome analysis of 206 SOT recipients following HCT challenges the validity of the frequently stated comparable outcome with recipients without prior HCT. SOT recipients after HCT are younger and have a higher mortality and morbidity in comparison with “standard” recipients. Rejection rates for SOT recipients following HCT appear to be lower for all organs, except for liver transplantation. In the setting of liver transplantation following HCT, mortality for recipients of deceased donor grafts appears to be exceptionally high, although experience with grafts of living donors are favourable. Morbidity was mostly associated with infectious and malignant complications. Of note some SOT recipients who received solid organ donation from the same HCT donor were able to achieve successful withdrawal of immune suppression. Despite limited follow-up, recipients with prior HCT show a different course after SOT, necessitating attention and closer follow-up.
has issue date	2018-08-06(xsd:dateTime)
bibo:doi	10.1038/s41409-018-0255-9
bibo:pmid	30082851
has license	no-cc
sha1sum (hex)	2cbe558ea57c5d930faa6dd1450d89abf04fa3bd
schema:url	https://doi.org/10.1038/s41409-018-0255-9
resource representing a document's title	Solid organ transplantation following allogeneic haematopoietic cell transplantation: experience from a referral organ transplantation center and systematic review of literature
has PubMed Central identifier	PMC7092162
has PubMed identifier	30082851
schema:publication	Bone Marrow Transplant
resource representing a document's body	covid:2cbe558ea57c5d930faa6dd1450d89abf04fa3bd#body_text
is schema:about of	named entity 'systematically' named entity 'prior' named entity 'donor' named entity 'organ transplantation' covid:arg/2cbe558ea57c5d930faa6dd1450d89abf04fa3bd named entity 'cell' named entity 'liver transplantation' named entity 'developing' named entity 'Despite' named entity 'malignancies' named entity 'received' named entity 'SOT' named entity 'SOT' named entity 'haematopoietic' named entity 'SOT' named entity 'SOT' named entity 'morbidity' named entity 'Solid organ transplantation' named entity 'organ transplantation' named entity 'haematopoietic' named entity 'organ transplantation' named entity 'donor' named entity 'GVHD' named entity 'pulmonary function' named entity 'hematopoietic stem cell transplant' named entity 'hematopoietic cell' named entity 'follow-up' named entity 'LTX' named entity 'cerebral oedema' named entity 'renal transplant' named entity 'mortality rates' named entity 'SOT' named entity 'cyclophosphamide' named entity 'malignant disease' named entity 'weaning' named entity 'organ' named entity 'kidney' named entity 'cirrhosis' named entity 'reported cases' named entity 'LTX' named entity 'SOT' named entity 'ESRD' named entity 'organ failure' named entity 'LTX' named entity 'malignancy' named entity 'calcineurin inhibitors' named entity 'HSCT' named entity 'tongue cancer' named entity 'receptor' named entity 'SOT' named entity 'hematopoietic stem cell donor' named entity 'SOT' named entity 'prognosis' named entity 'TNF' named entity 'KTX' named entity 'post-mortem examination' named entity 'relapse' named entity 'sepsis' named entity 'remission' named entity 'KTX' named entity 'myxofibrosarcoma' named entity 'heart failure' named entity 'extracorporeal photopheresis' named entity 'ESRD' named entity 'current literature' named entity 'lung' named entity 'KTX' named entity 'treatment modality'

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