About: Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine
Creator	Chen, Lizhu Hong, Xiaoyun Liu, Zhenguo Wei, Liangming Wu, Fei Wu, Zaozhan Yuan, Weien
Source	PMC
abstract	Microneedles were first conceptualized for drug delivery many decades ago, overcoming the shortages and preserving the advantages of hypodermic needle and conventional transdermal drug-delivery systems to some extent. Dissolving and biodegradable microneedle technologies have been used for transdermal sustained deliveries of different drugs and vaccines. This review describes microneedle geometry and the representative dissolving and biodegradable microneedle delivery methods via the skin, followed by the fabricating methods. Finally, this review puts forward some perspectives that require further investigation.
has issue date	2013-09-04(xsd:dateTime)
bibo:doi	10.2147/dddt.s44401
bibo:pmid	24039404
has license	cc-by-nc
sha1sum (hex)	2b5a2503522ac52b24f3475d69719626993d9dab
schema:url	https://doi.org/10.2147/dddt.s44401
resource representing a document's title	Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine
has PubMed Central identifier	PMC3771849
has PubMed identifier	24039404
schema:publication	Drug Des Devel Ther
resource representing a document's body	covid:2b5a2503522ac52b24f3475d69719626993d9dab#body_text
is schema:about of	named entity 'DRUG' named entity 'DRUG DESIGN' named entity 'THERAPY' named entity 'MEDICAL RESEARCH' named entity 'DEVELOPMENT' named entity 'drug' named entity 'TECHNOLOGIES' named entity 'MICRONEEDLE' named entity 'SCIENTIFIC' named entity 'SUSTAINED' named entity 'DELIVERY' named entity 'VACCINE' named entity 'OPEN' named entity 'TEXT' named entity 'DISSOLVING' named entity 'I E' named entity 'BIODEGRADABLE' named entity 'TRANSDERMAL' named entity 'ARTICLE' named entity 'COM' named entity 'MANUSCRIPT' named entity 'SUBMIT' named entity 'WWW' named entity 'ACCESS' named entity 'scientific' named entity 'sustained release' named entity 'patient compliance' named entity 'encapsulation' named entity 'drug delivery' named entity 'drug-delivery' named entity 'microparticles' named entity 'bovine serum albumin' named entity 'self-dissolving' named entity 'polymer' named entity 'cutaneous cancers' named entity 'drug administration' named entity 'macromolecules' named entity 'nanometers' named entity 'Eligard' named entity 'amylopectin' named entity 'genetic immunization' named entity 'vaccine' named entity 'insulin' named entity 'DNA vaccines' named entity 'patent' named entity 'carboxymethyl cellulose' named entity 'permeation' named entity 'vaccine' named entity 'sustained-release' named entity 'pig' named entity 'immunogenicity' named entity 'micropiles' named entity 'microsurgery' named entity 'hydrolysis' named entity 'biodegradable polymer' named entity 'permeability' named entity 'lymphatic vessels' named entity 'passive diffusion' named entity 'PLGA' named entity 'insulin' named entity 'growth hormones' named entity 'microanatomy' named entity 'blood vessels' named entity 'polydimethylsiloxane' named entity 'maleic anhydride' named entity 'interstitial fluid' named entity 'biodegradable' named entity 'sugar' named entity 'liver' named entity 'chondroitin sulfate' named entity 'transdermal drug' named entity 'adjuvants' named entity 'porous' named entity 'PLGA' named entity 'polymers'

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