About: Transformation of the Taiwan Biobank 3.0: vertical and horizontal integration

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Transformation of the Taiwan Biobank 3.0: vertical and horizontal integration
Creator	Fan, Chien-Te Lin, Jui-Chu Hsiao, Wei-Wen
Source	Medline; PMC
abstract	Researchers expect a high quality of biospecimens/data and value-added services from biobanks. Therefore, the concept of “biobank 3.0” was introduced so that biobanks could better meet the needs of stakeholders and maintain sustainable operations. Theoretically, the Taiwan Biobank (TWB) has already gone through the concepts of biobank 1.0 and 2.0. However, three challenges still need to be addressed before it can be transformed into a new generation of the TWB (namely, the TWB 3.0): (1) the difficulty of integrating other biobanks’ resources, (2) the efficiency and effectiveness of the release and use of biospecimens/data, and (3) the development of income and revenue models of sustainability. To address these issues, this paper proposes a framework for the TWB 3.0 transformation based on a dual-pillar approach composed of a “physically” vertical integration driven by the TWB and a “virtually” horizontal network led by the National Health Research Institutes (NHRI) of Taiwan. Using prominent biobanks such as the Biobanking and BioMolecular Resources Research Infrastructure-European Research Infrastructure Consortium (BBMRI-ERIC), the UK Biobank, and the National Institutes of Health (NIH)’s All of Us Research Program as models, the TWB can strengthen its on-going TWB 2.0 operations in regional and/or international collaboration, increase the value of data collected and develop closer relationships with biobank participants and users. To these ends, the authors highlight key issues that include, but are not limited to, the harmonization of relevant ELSI standards for various biobanks’ integrations; the value-added services and the efficiency of Big Data Era related research and/or precision medicine development, and financial concerns related to biobank sustainability. This paper concludes by discussing how greater participant engagement and the uptake of Information Technology (IT) and Artificial Intelligence (AI) applications can be used in partnership with vertical and horizontal integration as part of a four-pronged approach to promote biobank sustainability, and facilitate the TWB 3.0 transformation.
has issue date	2020-08-06(xsd:dateTime)
bibo:doi	10.1186/s12967-020-02451-4
bibo:pmid	32762757
has license	cc-by
sha1sum (hex)	2a39aedd5394c8fb01cbd9304bb4f16f856d6c16
schema:url	https://doi.org/10.1186/s12967-020-02451-4
resource representing a document's title	Transformation of the Taiwan Biobank 3.0: vertical and horizontal integration
has PubMed Central identifier	PMC7406956
has PubMed identifier	32762757
schema:publication	J Transl Med
resource representing a document's body	covid:2a39aedd5394c8fb01cbd9304bb4f16f856d6c16#body_text
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