About: Determination of 5′-leader sequences from radically disparate strains of porcine reproductive and respiratory syndrome virus reveals the presence of highly conserved sequence motifs

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About: Determination of 5′-leader sequences from radically disparate strains of porcine reproductive and respiratory syndrome virus reveals the presence of highly conserved sequence motifs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Determination of 5′-leader sequences from radically disparate strains of porcine reproductive and respiratory syndrome virus reveals the presence of highly conserved sequence motifs
Creator	Bøtner, A Nielsen, J Storgaard, T Oleksiewicz, M
Source	Medline; PMC
abstract	We determined the untranslated 5′-leader sequence for three different isolates of porcine reproductive and respiratory syndrome virus (PRRSV): pathogenic European- and American-types, as well as an American-type vaccine strain. 5′-leader from European- and American-type PRRSV differed in length (220 and 190 nt, respectively), and exhibited only approximately 50% nucleotide homology. Nevertheless, highly conserved areas were identified in the leader of all 3 PRRSV isolates, which constitute candidate motifs for binding of protein(s) involved in viral replication. These comparative data provide a priori knowledge for mutational identification of virulence determinants in the 5′ nontranslated part of the PRRSV genome.
has issue date	2014-05-18(xsd:dateTime)
bibo:doi	10.1007/s007050050560
bibo:pmid	10416379
has license	no-cc
sha1sum (hex)	29bfdcefcceeb8d155f385ecd28a487c8b950514
schema:url	https://doi.org/10.1007/s007050050560
resource representing a document's title	Determination of 5′-leader sequences from radically disparate strains of porcine reproductive and respiratory syndrome virus reveals the presence of highly conserved sequence motifs
has PubMed Central identifier	PMC7086836
has PubMed identifier	10416379
schema:publication	Arch Virol
resource representing a document's body	covid:29bfdcefcceeb8d155f385ecd28a487c8b950514#body_text
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