About: COVID‐19 Viral Load in the Severity of and Recovery from Olfactory and Gustatory Dysfunction

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About: COVID‐19 Viral Load in the Severity of and Recovery from Olfactory and Gustatory Dysfunction Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID‐19 Viral Load in the Severity of and Recovery from Olfactory and Gustatory Dysfunction
Creator	Fung, Kitty Kong, Hong Tong, Michael Chow, Eudora Hospital, Christian Tso, Eugene Chau, Sandy Cho, Ryan Yeung, Zenon Abdullah, Victor Hospital, O Ku, Peter Kwan, Tseung Hui, Thomas Kung, K Leung, Erica To, Zion Tsang, Steven Van Hasselt, Andrew
Source	Medline; PMC
abstract	OBJECTIVES: This study investigated olfactory and gustatory dysfunction in COVID‐19 patients, and their correlations with viral load evaluation. METHODS: This was a prospective cross‐sectional cohort study of 143 symptomatic patients being screened for SARS‐coronavirus 2 (SARS‐CoV‐2) invited to participate. The clinical data of 83 confirmed COVID‐19 subjects were collected, with 60 patients who were symptomatic but negative for COVID‐19 recruited as controls. The prevalence and severity of and recovery time for olfactory and gustatory dysfunction, and cycle threshold (Ct) values from a SARS‐CoV‐2 polymerase chain reaction (PCR) assay of nasopharyngeal and deep throat swabs were collected. Their correlations with Ct values were reported. RESULTS: Thirty‐nine (47.0%) and thirty‐six (43.4%) COVID‐19 patients reported olfactory and gustatory dysfunction, respectively. The results of one‐way ANOVA did not show statistically significant relationships between the Ct values and severity of olfactory and gustatory dysfunction (p = 0.780 and p = 0.121, respectively). Among the COVID‐19 patients who reported smell and taste loss, 28/39 (71.8%) and 30/36 (83.3%) experienced complete recovery, respectively. The mean recovery time was 10.3 ± 8.1 days for olfactory dysfunction and 9.5 ± 6.8 days for gustatory dysfunction. The recovery time was not correlated with the Ct values (Pearson correlation coefficient: smell: ‐0.008, p = 0.968; taste: ‐0.015, p = 0.940). CONCLUSION: There is a high prevalence of olfactory and gustatory dysfunction in COVID‐19. However, the severity of and recovery from these symptoms have no correlations with the viral load of SARS‐CoV‐2. This article is protected by copyright. All rights reserved.
has issue date	2020-08-13(xsd:dateTime)
bibo:doi	10.1002/lary.29056
bibo:pmid	32794209
has license	no-cc
sha1sum (hex)	26337623f4c9c32b0c110280f02de27e64f3bcb4
schema:url	https://doi.org/10.1002/lary.29056
resource representing a document's title	COVID‐19 Viral Load in the Severity of and Recovery from Olfactory and Gustatory Dysfunction
has PubMed Central identifier	PMC7436903
has PubMed identifier	32794209
schema:publication	Laryngoscope
resource representing a document's body	covid:26337623f4c9c32b0c110280f02de27e64f3bcb4#body_text
is schema:about of	named entity 'authors' named entity 'Viral' named entity 'Gustatory' named entity 'United Christian Hospital' named entity 'Tseung Kwan O Hospital' named entity 'Viral Load' named entity 'Viral Load' named entity 'Olfactory' named entity 'COVID-19' named entity 'Anosmia' named entity 'COVID' named entity 'olfactory' named entity 'human health' named entity 'dyspnea' named entity 'central nervous' named entity 'cough' named entity 'ACE2' named entity 'olfactory' named entity 'olfactory dysfunction' named entity 'nasopharyngeal' named entity 'sputum' named entity 'viral load' named entity 'olfactory bulb' named entity 'SARS-CoV-2' named entity 'ageusia' named entity 'dyspnea' named entity 'olfactory dysfunction' named entity 'intensive care' named entity 'olfactory' named entity 'dyspnea' named entity 'SARS-CoV-2' named entity 'epithelium' named entity 'symptom' named entity 'expectoration' named entity 'olfactory' named entity 'statistically significant' named entity 'Subgroup analysis' named entity 'SARS-CoV-2' named entity 'symptom' named entity 'SARS-CoV-2' named entity 'olfactory' named entity 'gustatory' named entity 'gustatory' named entity 'viral load' named entity 'demographic characteristics' named entity 'cough' named entity 'nucleic acid' named entity 'recall bias' named entity 'nasopharyngeal' named entity 'infection' named entity 'COVID' named entity 'gustatory' named entity 'gustatory' named entity 'Rhinorrhea' named entity '11.9' named entity 'control group' named entity 'viral illness' named entity 'gustatory' named entity 'fever' named entity 'gustatory' named entity 'viral load' named entity '26 men' named entity 'purulent'

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