About: Diagnostic evaluation of assays for detection of antibodies against porcine epidemic diarrhea virus (PEDV) in pigs exposed to different PEDV strains

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Diagnostic evaluation of assays for detection of antibodies against porcine epidemic diarrhea virus (PEDV) in pigs exposed to different PEDV strains Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Diagnostic evaluation of assays for detection of antibodies against porcine epidemic diarrhea virus (PEDV) in pigs exposed to different PEDV strains
Creator	Wang, Chong Zhang, Jianqiang Opriessnig, Tanja Lavazza, Antonio Lelli, Davide Moreno, Ana Bøtner, Anette Strandbygaard, Bertel Gerber, Priscilla Perulli, Simona Comtet, Loic Pourquier, Philippe Roche, Mickael
Source	Elsevier; Medline; PMC
abstract	Abstract Porcine epidemic diarrhea virus (PEDV) has caused economic losses in the Americas, Asia and Europe in recent years. Reliable serological assays are essential for epidemiological studies and vaccine evaluation. The objective of this study was to compare the ability of five enzyme-linked immunosorbent assays (ELISAs) to detect antibodies against different PEDV strains in pig serum. A total of 732 serum samples from North American or European pigs were tested. Samples included experimental samples from pigs infected with classical (G1a PEDV) or variant genogroup 1 PEDV (G1b PEDV), pandemic genogroup 2 PEDV (G2b PEDV) or non-infected controls. Field samples from herds with confirmed or unknown PEDV exposure were also used. Three indirect ELISAs based on G2b antigens (ELISAs 1, 2 and 3), a competitive ELISA based on the G2b antigen (ELISA 4) and a competitive ELISA based on the G1a antigen (ELISA 5) were compared. Overall, the tests had a moderate agreement (κ=0.61). G1a PEDV infected pigs were earliest detected by ELISA 3, G1b PEDV infected pigs were earliest detected by ELISAs 4 and 5 and the performance of all tests was similar for the G2b PEDV group. ELISA 1 showed the overall lowest detection on experimentally and field derived samples. Diagnostic sensitivity and specificity with a 95% probability interval were estimated to be 68.2% (62.1–74.4%) and 97.5% (95.2–99.0%) for ELISA 1, 73.7% (71.5–79.6%) and 98.4% (96.6–99.5%) for ELISA 2, 86.2% (81.1–90.6%) and 91.6% (87.7–94.8%) for ELISA 3, 78.3% (72.8–83.5%) and 99.7% (98.2–100%) for ELISA 4, and 93.5% (90.3–96.0%) and 91.2% (83.8–97.9%) for ELISA 5. Differences in detection among assays seem to be more related to intrinsic factors of an assay than to the PEDV antigen used.
has issue date	2016-12-01(xsd:dateTime)
bibo:doi	10.1016/j.prevetmed.2016.11.005
bibo:pmid	27931933
has license	els-covid
sha1sum (hex)	2490a12ef4b700055d34bde4325a59ca90b8186e
schema:url	https://doi.org/10.1016/j.prevetmed.2016.11.005
resource representing a document's title	Diagnostic evaluation of assays for detection of antibodies against porcine epidemic diarrhea virus (PEDV) in pigs exposed to different PEDV strains
has PubMed Central identifier	PMC7126628
has PubMed identifier	27931933
schema:publication	Preventive Veterinary Medicine
resource representing a document's body	covid:2490a12ef4b700055d34bde4325a59ca90b8186e#body_text
is schema:about of	named entity 'STRAINS' named entity 'DIFFERENT' named entity 'G2b' named entity 'specificity' named entity 'antigens' named entity 'G2b' named entity 'antibodies' covid:arg/2490a12ef4b700055d34bde4325a59ca90b8186e named entity 'ANTIBODIES' named entity 'ANTIBODIES' named entity 'EXPERIMENTAL' named entity 'VACCINE EVALUATION' named entity 'TESTS' named entity 'TOTAL' named entity 'USED' named entity 'UNKNOWN' named entity 'RELATED' named entity '99.5' named entity 'CAUSED' named entity 'SENSITIVITY AND SPECIFICITY' named entity 'PANDEMIC' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'DETECTION' named entity 'INFECTED' named entity 'DETECTED' named entity 'VARIANT' named entity 'ESSENTIAL' named entity 'OBJECTIVE' named entity 'NORTH AMERICAN' named entity 'BASED' named entity 'AMERICAS' named entity 'INCLUDED' named entity 'DERIVED' named entity 'ELISAS' named entity 'MODERATE AGREEMENT' named entity 'RECENT' named entity 'ENZYME-LINKED IMMUNOSORBENT ASSAYS' named entity 'ESTIMATED' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'DETECTION' named entity 'ABILITY' named entity 'TESTED' named entity 'SEROLOGICAL' named entity 'PIG' named entity 'ANTIGENS' named entity 'EXPOSED TO' named entity 'DIAGNOSTIC EVALUATION' named entity 'INDIRECT' named entity 'ANTIGEN' named entity 'INTRINSIC FACTORS' named entity 'INTERVAL' named entity 'SERUM' named entity 'PIGS' named entity 'NON-INFECTED' named entity 'ASIA' named entity 'FIELD' named entity 'CONFIRMED' named entity 'ASSAY' named entity '2896' named entity '100%' named entity 'OVERALL' named entity 'EUROPE' named entity '2887' named entity 'ELISA' named entity 'CLASSICAL' named entity 'YEARS' named entity 'GROUP' named entity 'COMPARED' named entity 'EPIDEMIOLOGICAL STUDIES'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software