About: Association of diabetes and hypertension with disease severity in covid-19 patients: a systematic literature review and exploratory meta-analysis

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About: Association of diabetes and hypertension with disease severity in covid-19 patients: a systematic literature review and exploratory meta-analysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Association of diabetes and hypertension with disease severity in covid-19 patients: a systematic literature review and exploratory meta-analysis
Creator	Agarwal, Nidhi Bajpai, Ram Parveen, Rizwana Sehar, Nouroz
Source	Elsevier; Medline; PMC
abstract	Abstract Aim The novel coronavirus infection (COVID-19), now a worldwide public health concern is associated with varied fatality. Patients with chronic underlying conditions like diabetes and hypertension have shown worst outcomes. The understanding of the association might be helpful in early vigilant monitoring and better management of COVID-19 patients at high risk. The aim of the meta-analysis was to assess the association of diabetes and hypertension with severity of disease. Methods A literature search was conducted using the databases PubMed and Cochrane until March 31, 2020. Seven studies were included in the meta- analysis, including 2018 CIVID-19 patients. Results Diabetes was lower in the survivors (OR: 0.56; 95%CI: 0.35-0.90; p=0.017; I2 : 0.0%) and non-severe (OR: 1.66; 95%CI: 1.20-2.30; p=0.002; I2 : 0.0%) patients. No association of diabetes was found with ICU care. Hypertension was positively associated with death (OR: 0.49; 95%CI: 0.34-0.73; p=0.000; I2 : 0.0%), ICU care (OR: 0.42; 95%CI: 0.22-0.81; p=0.009; I2 : 0.0%) and severity (OR: 2.69; 95%CI: 1.27-5.73; p=0.01; I2 : 52.4%). Conclusions Our findings suggest that diabetes and hypertension have a negative effect on health status of COVID-19 patients. However, large prevalence studies demonstrating the consequences of comorbid diabetes and hypertension are urgently needed to understand the magnitude of these vexatious comorbidities.
has issue date	2020-07-03(xsd:dateTime)
bibo:doi	10.1016/j.diabres.2020.108295
bibo:pmid	32623032
has license	els-covid
sha1sum (hex)	231954871ce8c9516bb4a29f9a20059215759cc6
schema:url	https://doi.org/10.1016/j.diabres.2020.108295
resource representing a document's title	Association of diabetes and hypertension with disease severity in covid-19 patients: a systematic literature review and exploratory meta-analysis
has PubMed Central identifier	PMC7332452
has PubMed identifier	32623032
schema:publication	Diabetes Res Clin Pract
resource representing a document's body	covid:231954871ce8c9516bb4a29f9a20059215759cc6#body_text
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