About: Recovery rate and factors associated with smell and taste disruption in patients with coronavirus disease 2019

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Recovery rate and factors associated with smell and taste disruption in patients with coronavirus disease 2019
Creator	Barreira-Fernandez, Pilar Parente-Arias, Pablo Patiño-Castiñeira, Berta Quintana-Sanjuas, Ana
Source	Elsevier; PMC
abstract	PURPOSE: To determine the occurrence of olfactory and gustatory disruptions in COVID-19 patients, their association with demographic and clinical features and prognosis. MATERIAL AND METHODS: This observational cohort study involved consecutively diagnosed COVID-19 patients tested between March the 3rd 2020 and March the 24th 2020, in a geographically defined cohort area. All COVID-19 patients were evaluated in a University Hospital. The primary outcome of interest is the prevalence of smell and taste alterations, factors associated and recovery rate. Univariate and multivariate analysis by logistic regression was performed to detect factors associated to these symptoms. RESULTS: 151 patients were included and 99 (65.3%) reported olfactory or gustatory symptoms. Olfactory dysfunction was reported by 75 patients (49.7%). Isolated anosmia was found in 2 patients (1.3%). Gustatory dysfunction was reported by 91 patients (60.3%). Factors associated with higher prevalence of smell dysfunction included age, sex, and comorbidities. The time to smell disruption development was significantly shorter in mild to moderate patients than in severe patients (p = 0.043). In 85.3% of patients with smell disruption, the symptom had been resolved in the first 2 months. 14.7% of patients remained symptomatic after 3 months of follow-up. CONCLUSIONS: Olfactory and gustatory dysfunction was common in COVID-19 patients. Smell disruption has high recovery rate and was associated with age, sex, and clinical severity. It may be beneficial to investigate the appearance of taste and/or smell disruptions in individual patients, with respect to diagnosis and prognosis.
has issue date	2020-07-14(xsd:dateTime)
bibo:doi	10.1016/j.amjoto.2020.102648
has license	no-cc
sha1sum (hex)	221a940b983e96e7b4668b2225f1eab8372920b3
schema:url	https://doi.org/10.1016/j.amjoto.2020.102648
resource representing a document's title	Recovery rate and factors associated with smell and taste disruption in patients with coronavirus disease 2019
has PubMed Central identifier	PMC7358151
schema:publication	Am J Otolaryngol
resource representing a document's body	covid:221a940b983e96e7b4668b2225f1eab8372920b3#body_text
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