About: Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus

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About: Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus
Creator	Escribano, J Borca, M Castañón, S Gil, F Gómez, N Ordás, R Wigdorovitz, A
Source	Medline; PMC
abstract	Transgenic plants represent an inexpensive alternative to classical fermentation systems for production of recombinant subunit vaccines. Transgenic potato plants were created that express the N-terminal domain of the glycoprotein S (N-gS) from Transmissible gastroenteritis coronavirus (TGEV), containing the major antigenic sites of the protein. Extracts from potato tubers expressing N-gS were inoculated intraperitoneally to mice, and the vaccinated mice developed serum IgG specific for TGEV. Furthermore, when potato tubers expressing N-gS were fed directly to mice, they developed serum antibodies specific for gS protein, demonstrating the oral immunogenicity of the plant derived spike protein from TGEV.
has issue date	2000-01-01(xsd:dateTime)
bibo:doi	10.1007/s007050070087
bibo:pmid	11003480
has license	no-cc
sha1sum (hex)	1f6ebfe10bb34747fb91008cf07d26b6e9e1614a
schema:url	https://doi.org/10.1007/s007050070087
resource representing a document's title	Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus
has PubMed Central identifier	PMC7086604
has PubMed identifier	11003480
schema:publication	Arch Virol
resource representing a document's body	covid:1f6ebfe10bb34747fb91008cf07d26b6e9e1614a#body_text
is schema:about of	named entity 'systems' named entity 'inoculated' named entity 'sows' named entity 'N-terminal domain' named entity 'site A' named entity 'SPIKE PROTEIN' named entity 'IMMUNOGENICITY' named entity 'IMMUNOGENICITY' named entity 'MAPPED' named entity 'RECOMBINANT' named entity 'SPECIFIC' named entity 'HIGH RATE' named entity '5B10' named entity 'TRANSMISSIBLE GASTROENTERITIS CORONAVIRUS' named entity 'ACUTE DIARRHEA' named entity 'ORDER' named entity 'PREGNANT' named entity 'TROUGH' named entity 'VACCINATED' named entity 'RELEVANT' named entity 'CONTAINING' named entity 'SYSTEMS' named entity 'AFFECTED' named entity 'PROTECTIVE IMMUNITY' named entity 'SUBUNIT VACCINES' named entity 'ORAL' named entity 'NEUTRALIZING ANTIBODIES' named entity 'PLANT' named entity 'SPIKE PROTEIN' named entity 'FARMS' named entity 'ANTIBODIES SPECIFIC' named entity 'PROTEIN ' named entity 'REPORT' named entity 'MORTALITIES' named entity 'MICE' named entity 'HAVE' named entity 'DESCRIBED' named entity 'SOWS' named entity 'REPRESENT' named entity 'EPITOPES' named entity 'DIRECTLY' named entity 'DERIVED' named entity 'DOMAIN' named entity 'MILK' named entity 'FED' named entity 'GLOBULAR' named entity 'CAUSATIVE AGENT' named entity 'MAJOR' named entity 'BRIEF' named entity 'SWINE' named entity 'EXPRESS' named entity 'COLOSTRUM' named entity 'TRANSGENIC PLANTS' named entity 'PLANTS' named entity 'PROTEIN ' named entity 'ORAL' named entity 'DERIVED' named entity 'POTATO' named entity 'PROTEIN' named entity 'PRODUCTION' named entity 'CREATED' named entity 'SITES' named entity 'PASSIVE' named entity 'IGG' named entity 'DISEASE' named entity 'TRANSGENIC POTATO' named entity 'N-TERMINAL ' named entity 'DIRECTED' named entity 'PROTECTION' named entity 'ALTERNATIVE' named entity 'TRANSMISSIBLE GASTROENTERITIS CORONAVIRUS' named entity 'PLANT' named entity 'SITE' named entity 'VIRUS' named entity 'EXTRACTS'

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