About: Late viral or bacterial respiratory infections in lung transplanted patients: impact on respiratory function

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Late viral or bacterial respiratory infections in lung transplanted patients: impact on respiratory function Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Late viral or bacterial respiratory infections in lung transplanted patients: impact on respiratory function
Creator	Lescure, François-Xavier Visseaux, Benoit Yazdanpanah, Yazdan Birgy, André Castier, Yves Dauriat, Gaelle Dubert, Marie Fidouh, Nadhira Grall, Nathalie Mal, Hervé Metivier, Anne-Cécile Mordant, Pierre Thabut, Gabriel
Source	Medline; PMC
abstract	BACKGROUND: Respiratory infections are a major threat for lung recipients. We aimed to compare with a monocentric study the impact of late viral and bacterial respiratory infections on the graft function. METHODS: Patients, who survived 6 months or more following lung transplantation that took place between 2009 and 2014, were classified into three groups: a viral infection group (VIG) (without any respiratory bacteria), a bacterial infection group (BIG) (with or without any respiratory viruses), and a control group (CG) (no documented infection). Chronic lung allograft dysfunction (CLAD) and acute rejection were analysed 6 months after the inclusion in the study. RESULTS: Among 99 included lung recipients, 57 (58%) had at least one positive virological respiratory sample during the study period. Patients were classified as follows: 38 in the VIG, 25 in the BIG (among which 19 co-infections with a virus) and 36 in the CG. The BIG presented a higher initial deterioration in lung function (p = 0.05) than the VIG. But 6 months after the infection, only the VIG presented a median decrease of forced expiratory volume in 1 s; − 35 mL (IQR; − 340; + 80) in the VIG, + 140 mL (+ 60;+ 330) in the BIG and + 10 (− 84;+ 160) in the CG, p < 0.01. Acute rejection was more frequent in the VIG (n = 12 (32%)), than the BIG (n = 6 (24%)) and CG (n = 3 (8%)), p < 0.05, despite presenting no more CLAD (p = 0.21). CONCLUSIONS: Despite a less severe initial presentation, single viral respiratory infections seem to lead to a greater deterioration in lung function, and to more acute rejection, than bacterial infections.
has issue date	2020-02-24(xsd:dateTime)
bibo:doi	10.1186/s12879-020-4877-3
bibo:pmid	32093612
has license	cc-by
sha1sum (hex)	1e0851ed44e0459ff83448af23b81560a41ede72
schema:url	https://doi.org/10.1186/s12879-020-4877-3
resource representing a document's title	Late viral or bacterial respiratory infections in lung transplanted patients: impact on respiratory function
has PubMed Central identifier	PMC7041086
has PubMed identifier	32093612
schema:publication	BMC Infect Dis
resource representing a document's body	covid:1e0851ed44e0459ff83448af23b81560a41ede72#body_text
is schema:about of	named entity 'impact' named entity 'analysed' covid:arg/1e0851ed44e0459ff83448af23b81560a41ede72 named entity 'dysfunction' named entity 'monocentric' named entity 'viruses' named entity 'control group' named entity 'respiratory infections' named entity 'respiratory infections' named entity 'lung' named entity 'virus' named entity 'blood tests' named entity 'respiratory infections' named entity 'graft rejection' named entity 'nasopharyngeal swabs' named entity 'aspirates' named entity 'rhinovirus' named entity 'respiratory infections' named entity 'picornavirus' named entity 'herpetic' named entity 'internal method' named entity 'lung' named entity 'viral infections' named entity 'immunosuppression' named entity 'asymptomatic' named entity 'spirometry' named entity 'infection' named entity 'virus' named entity 'Influenza' named entity 'lung transplantation' named entity 'picornavirus' named entity 'CFU' named entity 'meta-analysis' named entity 'metapneumovirus' named entity 'sample size' named entity 'lung function' named entity 'molecular biology' named entity 'bacterial infections' named entity 'higher risk' named entity 'acute rejection' named entity 'viral infections' named entity 'virus' named entity 'co-infected' named entity 'aspirates' named entity 'logistic regression' named entity 'Clinical presentation' named entity 'incidence rate' named entity 'Secondary endpoints' named entity 'infection' named entity 'lung' named entity 'stenosis' named entity 'initial infection' named entity 'viruses' named entity 'PCR test' named entity 'forced expiratory volume' named entity 'chest X-ray' named entity 'ischemic' named entity 'FEV' named entity 'nasopharyngeal swabs' named entity 'cell cultures' named entity 'bacterial infections' named entity 'pulmonary function' named entity 'respiratory tract infections' named entity 'lung transplantation' named entity 'statistical analysis' named entity 'LTRs' named entity 'Claude Bernard' named entity 'respiratory infections' named entity 'rhinovirus'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software