About: Vapor H2O2 sterilization as a decontamination method for the reuse of N95 respirators in the COVID-19 emergency

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About: Vapor H2O2 sterilization as a decontamination method for the reuse of N95 respirators in the COVID-19 emergency Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Vapor H2O2 sterilization as a decontamination method for the reuse of N95 respirators in the COVID-19 emergency
Creator	Storm, Nadia Honko, Anna Griffiths, Anthony Avena, Laura Connolly, Rachel Downs, Sierra Emmal, Brandon Flynn, Nick Gardecki, Joseph Jones, Ralph Leung, Hui Mckay, Lindsay Muratoglu, Orhun Oral, Ebru Wannomae, Keith
Source	MedRxiv
abstract	There are a variety of methods routinely used in the sterilization of medical devices using hydrogen peroxide (H2O2) including vaporization, plasma generation and ionization. Many of these systems are used for sterilization and are validated for bioburden reduction using bacterial spores. Here, we explored the benefits of using vaporized H2O2 (VHP) treatment of N95 respirators for emergency decontamination and reuse to alleviate PPE shortages for healthcare workers in the COVID-19 emergency. The factors that are considered for the effective reuse of these respirators are the fit, the filter efficiency and the decontamination/disinfection level for SARS-CoV-2, which is the causative virus for COVID-19 and other organisms of concern in the hospital environment such as methicillin-resistant Staphylococcus aureus or Clostridium difficile. WE showed that the method did not affect fit or filter efficiency at least for one cycle and resulted in a >6 log reduction in bacterial spores and >3.8 log reduction in the infectious SARS-CoV2 load on N95 respirators.
has issue date	2020-04-16(xsd:dateTime)
bibo:doi	10.1101/2020.04.11.20062026
has license	medrxiv
sha1sum (hex)	1be38aef531314a0eb759ca6df9eb16dd1731af4
schema:url	https://doi.org/10.1101/2020.04.11.20062026
resource representing a document's title	Vapor H2O2 sterilization as a decontamination method for the reuse of N95 respirators in the COVID-19 emergency
resource representing a document's body	covid:1be38aef531314a0eb759ca6df9eb16dd1731af4#body_text
is schema:about of	named entity 'N95' named entity 'VHP' named entity 'VHP' named entity 'respirator' named entity 'Face Masks' named entity 'N95' named entity 'vaporization' named entity 'preprint' named entity 'VHP' named entity 'VHP' named entity 'VHP' named entity 'sterilization' named entity 'biosafety cabinet' named entity 'respirator' named entity 'essential amino acids' named entity 'spores' named entity 'ionization' named entity 'DMEM' named entity 'FDA' named entity 'VHP' named entity 'VHP' named entity 'Health and Safety' named entity 'vaporized hydrogen peroxide' named entity 'room temperature' named entity 'sterility assurance level' named entity 'respirator' named entity 'methicillin-resistant Staphylococcus aureus' named entity 'plastic' named entity 'hydrogen peroxide' named entity 'centrifugation' named entity 'virus' named entity 'sterilization' named entity 'N95 respirators' named entity 'pentane' named entity 'medRxiv' named entity 'NEIDL' named entity 'virus' named entity 'antimycotics' named entity 'Virus' named entity 'preprint' named entity 'sterility assurance level' named entity 'Steris' named entity 'disinfection' named entity 'Virus' named entity 'SAL' named entity 'preprint' named entity 'N95 respirators' named entity 'VHP' named entity 'DMEM' named entity 'preprint' named entity 'VHP' named entity 'SARS-CoV-2' named entity 'Public Health Emergency' named entity 'VHP' named entity 'face masks' named entity 'sterilant' named entity 'VERO cells' named entity 'Emergency Use Authorization' named entity 'virus' named entity 'CC-BY-NC-ND 4.0' named entity 'microorganisms' named entity 'healthcare workers' named entity 'VHP' named entity 'virus' named entity 'VHP' named entity 'N95' named entity 'plaque assay' named entity 'virus' named entity 'microcrystalline cellulose' named entity 'respirator' named entity 'Decontamination'

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