About: Prediction of Survival After Liver Transplantation for Chronic Severe Hepatitis B Based on Preoperative Prognostic Scores: A Single Center’s Experience in China

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About: Prediction of Survival After Liver Transplantation for Chronic Severe Hepatitis B Based on Preoperative Prognostic Scores: A Single Center’s Experience in China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Prediction of Survival After Liver Transplantation for Chronic Severe Hepatitis B Based on Preoperative Prognostic Scores: A Single Center’s Experience in China
Creator	Liang, Xiao Ma, Ae, Hong Ae, Jun Ae, Zheng-Xin Ae, Zhi-Ren Fu, A Guo-Shan, Ding Shi, A Wang, Ae Xiao-Min Wen-Yuan, Guo Zhi-Jia, Ni
source	PMC
abstract	BACKGROUND: The aim of this study was to estimate the utility of a preoperative model of end-stage liver disease (MELD) score and Child-Turcotte-Pugh (CTP) score in predicting the prognosis after othotopic liver transplantation (OLT) for chronic severe hepatitis B (CSHB) and explore the prognostic factors. METHODS: The outcome of 137 patients who underwent OLT using donors after cardiac death (DCDs) for CSHB in our center was reviewed retrospectively. Survival analysis was performed using the Kaplan-Meier method; the log-rank test was used for univariate analysis; and the Cox proportional hazards regression model was used for prognostic factors screening. RESULTS: The overall mortality rate was 33.6% (46/137); and 1-month, 6-month, 1-year, and 5-year patient survival rates were 75.8, 72.0, 71.0, and 60.1%, respectively. Most patients (33/46) died during the first month after OLT. The area under the curve values generated by the receiver operating characteristics curves were 0.82 [95% confidence interval (CI) 0.72–0.92] and 0.68 (95% CI 0.58–0.79), respectively (P < 0.01), for the MELD and CTP models in predicting 1-month mortality after OLT. Patients with a preoperative MELD score <33.8 or a CTP score <12.5 had significantly better prognosis than those with higher scores (P < 0.05). Other mortality predictors include hepatic encephalopathy, preoperative infection, serum creatinine ≥1.5 mg/dl. CONCLUSIONS: The MELD score was more efficient than the CTP score for evaluating the short-term prognosis in patients with CSHB undergoing OLT using DCDs, which should be taken into consideration during graft allocation.
has issue date	2009-08-20(xsd:dateTime)
bibo:doi	10.1007/s00268-009-0183-3
bibo:pmid	19693632
has license	no-cc
sha1sum (hex)	1b82d83469b9f1286f5c733bcc574747ea020805
schema:url	https://doi.org/10.1007/s00268-009-0183-3
resource representing a document's title	Prediction of Survival After Liver Transplantation for Chronic Severe Hepatitis B Based on Preoperative Prognostic Scores: A Single Center’s Experience in China
has PubMed Central identifier	PMC7102514
has PubMed identifier	19693632
schema:publication	World J Surg
resource representing a document's body	covid:1b82d83469b9f1286f5c733bcc574747ea020805#body_text
is schema:about of	named entity 'model' named entity 'prognostic' named entity 'SCORES' named entity '0.58' named entity 'CSHB' named entity 'CTP' named entity 'mortality rate' named entity 'prognosis' named entity 'patients' named entity 'mortality' named entity 'higher' named entity 'Kaplan-Meier' named entity 'factors' named entity 'univariate analysis' named entity 'mortality' named entity 'MELD' named entity 'serum creatinine' named entity 'hepatitis' named entity 'hepatic encephalopathy' named entity 'survival rates' named entity 'univariate analysis' named entity 'Cox proportional hazards regression' named entity 'China' named entity 'Liver Transplantation' named entity 'Prognostic' named entity 'OLT.' named entity 'patient' named entity 'hepatic encephalopathy' named entity 'survival rates' named entity 'etiology' named entity 'administrated' named entity 'anti-virus' named entity 'ROC curves' named entity 'CSHB' named entity 'clinical study' named entity 'hepatorenal syndrome' named entity 'anastomotic' named entity 'cirrhosis' named entity 'Survival analysis' named entity 'serum' named entity 'perfusion' named entity 'computed tomography' named entity 'MELD' named entity 'alcoholic hepatitis' named entity 'log-rank test' named entity 'ARDS' named entity 'Viral Hepatitis' named entity 'hepatitis' named entity 'hepatorenal syndrome' named entity 'log-rank test' named entity 'perfusion' named entity 'liver transplantation' named entity 'CSHB' named entity 'coma' named entity 'antigen' named entity 'blood pressure' named entity 'Lamivudine' named entity 'serum creatinine' named entity 'hepatitis C virus (HCV) infection' named entity 'liver failure' named entity 'survival rates' named entity 'viscosity solutions' named entity 'basic conditions' named entity 'liver disease' named entity 'albumin' named entity 'HBsAg' named entity 'MELD' named entity 'alanine aminotransferase' named entity 'diagnostic accuracy' named entity 'peritonitis'

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