About: Dynamic changes of serum SARS-Coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Dynamic changes of serum SARS-Coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Dynamic changes of serum SARS-Coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge
Creator	Zhao, Hong Chen, Weijun Xie, Lixin Chen, Liangan Fan, Baoxing Liu, Youning Tian, Qing Xiao, Yueyong
Source	Medline; PMC
abstract	OBJECTIVE: The intent of this study was to examine the recovery of individuals who had been hospitalized for severe acute respiratory syndrome (SARS) in the year following their discharge from the hospital. Parameters studied included serum levels of SARS coronavirus (SARS-CoV) IgG antibody, tests of lung function, and imaging data to evaluate changes in lung fibrosis. In addition, we explored the incidence of femoral head necrosis in some of the individuals recovering from SARS. METHODS: The subjects of this study were 383 clinically diagnosed SARS patients in Beijing, China. They were tested regularly for serum levels of SARS-CoV IgG antibody and lung function and were given chest X-rays and/or high resolution computerized tomography (HRCT) examinations at the Chinese PLA General Hospital during the 12 months that followed their release from the hospital. Those individuals who were found to have lung diffusion abnormities (transfer coefficient for carbon monoxide [D(L)CO] < 80% of predicted value [pred]) received regular lung function tests and HRCT examinations in the follow-up phase in order to document the changes in their lung condition. Some patients who complained of joint pain were given magnetic resonance imaging (MRI) examinations of their femoral heads. FINDINGS: Of all the subjects, 81.2% (311 of 383 patients) tested positive for serum SARS-CoV IgG. Of those testing positive, 27.3% (85 of 311 patients) were suffering from lung diffusion abnormities (D(L)CO < 80% pred) and 21.5% (67 of 311 patients) exhibited lung fibrotic changes. In the 12 month duration of this study, all of the 40 patients with lung diffusion abnormities who were examined exhibited some improvement of lung function and fibrosis detected by radiography. Of the individuals receiving MRI examinations, 23.1% (18 of 78 patients) showed signs of femoral head necrosis. INTERPRETATION: The lack of sero-positive SARS-CoV in some individuals suggests that there may have been some misdiagnosed cases among the subjects included in this study. Of those testing positive, the serum levels of SARS-CoV IgG antibody decreased significantly during the 12 months after hospital discharge. Additionally, we found that the individuals who had lung fibrosis showed some spontaneous recovery. Finally, some of the subjects developed femoral head necrosis.
has issue date	2005-01-08(xsd:dateTime)
bibo:doi	10.1186/1465-9921-6-5
bibo:pmid	15638943
has license	cc-by
sha1sum (hex)	18c21db94a22f1358057c6d797164ffe1585b395
schema:url	https://doi.org/10.1186/1465-9921-6-5
resource representing a document's title	Dynamic changes of serum SARS-Coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge
has PubMed Central identifier	PMC545044
has PubMed identifier	15638943
schema:publication	Respir Res
resource representing a document's body	covid:18c21db94a22f1358057c6d797164ffe1585b395#body_text
is schema:about of	named entity 'RECOVERING FROM' named entity 'recovery' named entity 'intent' named entity 'RESPIRATORY' named entity 'DYNAMIC' named entity 'PATIENTS' named entity 'CHANGES' named entity 'RADIOGRAPHY' named entity 'SARS' named entity 'HOSPITAL DISCHARGE' named entity 'FOLLOWING' named entity 'DISCHARGE' named entity 'RECOVERING FROM' named entity 'SARS CORONAVIRUS' named entity 'YEAR' named entity 'EVALUATE' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'IMAGING' named entity 'HOSPITALIZED' named entity 'LEVELS' named entity 'RESEARCH' named entity 'NECROSIS' named entity 'FEMORAL HEAD' named entity 'PULMONARY FUNCTION' named entity 'IGG' named entity 'STUDY' named entity 'CHANGES' named entity 'OBJECTIVE' named entity 'INCLUDED' named entity 'HOSPITAL' named entity 'SARS' named entity 'PARAMETERS' named entity 'IGG ANTIBODY' named entity 'ADDITION' named entity 'FEMORAL HEAD' named entity 'LUNG FIBROSIS' named entity 'TESTS' named entity 'LUNG FUNCTION' named entity 'INCIDENCE' named entity 'DATA' named entity 'TO EXAMINE' named entity 'RECOVERY' named entity 'SERUM' named entity 'INTENT' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'INDIVIDUALS' named entity 'THEIR' named entity 'CORONAVIRUS' named entity 'SERUM' named entity 'NECROSIS' covid:arg/18c21db94a22f1358057c6d797164ffe1585b395 named entity 'addition' named entity 'incidence' named entity 'SARS-CoV' named entity 'severe acute respiratory syndrome (SARS)' named entity 'SARS-CoV' named entity 'Severe acute respiratory syndrome (SARS)' named entity 'serum levels' named entity 'IgG' named entity 'SARS' named entity 'femoral head' named entity 'antibody' named entity 'one-way analysis of variance' named entity 'FVC' named entity 'IgG' named entity 'clinical diagnosis' named entity 'PCR' named entity 'pulmonary function' named entity 'avascular necrosis' named entity 'traction bronchiectasis' named entity 'SARS' named entity 'dry cough' named entity 'pulmonary fibrosis' named entity 'P.R. China'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software