About: Microvascular Disease Confers Additional Risk to COVID-19 Infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Microvascular Disease Confers Additional Risk to COVID-19 Infection
Creator	Vigerust, David Field Bale, Bradley Dnp, Doneen Doneen, Amy Field, Bradley Lynn, Amy
Source	Elsevier; Medline; PMC
abstract	The majority of fatalities thus far in the COVID-19 pandemic have been attributed to pneumonia. As expected, the fatality rate reported in China is higher in people with chronic pulmonary disease (6.3%) and those who have cancer (5.6%). According to the American College of Cardiology Clinical Bulletin “COVID-19 Clinical Guidance for the CV Care Team”, there is a significantly higher fatality rate in people who are elderly (8.0% 70-79 years; 14.8% ≥80 years), diabetic (7.3%), hypertensive (6.0%), or have known cardiovascular disease (CVD) (10.5%). We propose a biological reason for the higher mortality risk in these populations that is apparent. We further present a set of pathophysiological reasons for the heightened danger that could lead to therapies for enhanced management and prevention. MVD And COVID Abstract The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov2) results in COVID-19 which can lead to severe illness and death. The majority of fatalities thus far in the pandemic have been attributed to pneumonia. The overall mortality risk reported as of March 28, 2020 varies from 2.3% in China, 2.7% in Iran, and 0.5% in South Korea. As expected, the fatality rate reported in China is higher in people with chronic pulmonary disease (6.3%) and those who have cancer (5.6%). According to the American College of Cardiology Clinical Bulletin “COVID-19 Clinical Guidance for the CV Care Team”, there is a significantly higher fatality rate in people who are elderly (8.0% 70-79; 14.8% ≥80), diabetic (7.3%), hypertensive (6.0%), or have known cardiovascular disease (CVD) (10.5%). We propose a reason for the higher mortality risk in these populations that is not apparent. We further present a set of pathophysiological reasons for the heightened danger could lead to therapies for enhanced management and prevention.
has issue date	2020-06-15(xsd:dateTime)
bibo:doi	10.1016/j.mehy.2020.109999
bibo:pmid	32570168
has license	no-cc
sha1sum (hex)	17f3492967ea0c9648551100cc2a5ce49a7f3e3d
schema:url	https://doi.org/10.1016/j.mehy.2020.109999
resource representing a document's title	Microvascular Disease Confers Additional Risk to COVID-19 Infection
has PubMed Central identifier	PMC7294251
has PubMed identifier	32570168
schema:publication	Med Hypotheses
resource representing a document's body	covid:17f3492967ea0c9648551100cc2a5ce49a7f3e3d#body_text
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