About: No evidence of coronaviruses or other potentially zoonotic viruses in Sunda pangolins (Manis javanica) entering the wildlife trade via Malaysia

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About: No evidence of coronaviruses or other potentially zoonotic viruses in Sunda pangolins (Manis javanica) entering the wildlife trade via Malaysia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	No evidence of coronaviruses or other potentially zoonotic viruses in Sunda pangolins (Manis javanica) entering the wildlife trade via Malaysia
Creator	Hughes, Tom Thomas, Lee, Jimmy Japning, Jeffrine Kumar, Subbiah Lasimbang, Helen Lee, Mei-Ho Nathan, Senthilvel Peter, Daszak Ramirez, Diana Sitam, Frankie Vijay,
Source	BioRxiv
abstract	The legal and illegal trade in wildlife for food, medicine and other products is a globally significant threat to biodiversity that is also responsible for the emergence of pathogens that threaten human and livestock health and our global economy. Trade in wildlife likely played a role in the origin of COVID-19, and viruses closely related to SARS-CoV-2 have been identified in bats and pangolins, both traded widely. To investigate the possible role of pangolins as a source of potential zoonoses, we collected throat and rectal swabs from 334 Sunda pangolins (Manis javanica) confiscated in Peninsular Malaysia and Sabah between August 2009 and March 2019. Total nucleic acid was extracted for viral molecular screening using conventional PCR protocols used to routinely identify known and novel viruses in extensive prior sampling (>50,000 mammals). No sample yielded a positive PCR result for any of the targeted viral families – Coronaviridae, Filoviridae, Flaviviridae, Orthomyxoviridae and Paramyxoviridae. In light of recent reports of coronaviruses including a SARS-CoV-2 related virus in Sunda pangolins in China, the lack of any coronavirus detection in our ‘upstream’ market chain samples suggests that these detections in ‘downstream’ animals more plausibly reflect exposure to infected humans, wildlife or other animals within the wildlife trade network. While confirmatory serologic studies are needed, it is likely that Sunda pangolins are incidental hosts of coronaviruses. Our findings further support the importance of ending the trade in wildlife globally.
has issue date	2020-06-19(xsd:dateTime)
bibo:doi	10.1101/2020.06.19.158717
has license	biorxiv
sha1sum (hex)	17dba3d819679a6a4d8118ec3bf0c49fc53ed4a3
schema:url	https://doi.org/10.1101/2020.06.19.158717
resource representing a document's title	No evidence of coronaviruses or other potentially zoonotic viruses in Sunda pangolins (Manis javanica) entering the wildlife trade via Malaysia
schema:publication	bioRxiv
resource representing a document's body	covid:17dba3d819679a6a4d8118ec3bf0c49fc53ed4a3#body_text
is schema:about of	named entity 'zoonoses' named entity 'swabs' named entity 'SARS-CoV-2' named entity 'pangolins' named entity 'pangolins' named entity 'Sunda pangolins' named entity 'pathogens' named entity 'livestock' named entity 'trade in wildlife' named entity 'closely related' named entity 'Sunda pangolins' named entity 'China' named entity 'bat' named entity 'infection' named entity 'Borneo' named entity 'PCR' named entity 'zoonotic pathogens' named entity 'coronaviruses' named entity 'pangolins' named entity 'pangolins' named entity 'Sunda pangolins' named entity 'Manis javanica' named entity 'farmed animals' named entity 'pathogen' named entity 'USAID' named entity 'Sunda pangolin' named entity 'human health' named entity 'reverse transcription PCR' named entity 'PCR' named entity 'tris-acetate' named entity 'Sabah' named entity 'cDNA' named entity 'pangolins' named entity 'cDNA' named entity 'coronaviruses' named entity 'PCR' named entity 'phylogeographic' named entity 'gel electrophoresis' named entity 'University of California, Davis' named entity 'polyester' named entity 'Foster City' named entity 'Southeast Asian' named entity 'pangolins' named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'viruses' named entity 'Southeast Asian' named entity 'Malaysia' named entity 'International Union for Conservation of Nature' named entity 'contamination control' named entity 'Peninsular Malaysia' named entity 'pangolins' named entity 'Peninsular Malaysia' named entity 'SARS CoV2' named entity 'China' named entity 'PCR' named entity 'SARS-CoV-2' named entity '95% confidence interval' named entity 'viruses' named entity 'PCR' named entity 'Peninsular Malaysia' named entity 'wet markets' named entity 'Complementary DNA' named entity 'bat' named entity 'Latinne' named entity 'GPS' named entity 'Critically Endangered' named entity 'Guangdong province, China' named entity 'coronaviruses' named entity 'SARS-CoV' named entity 'pangolins' named entity 'biocontainment' named entity 'SARS-CoV'

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