About: Multiplex PCR analysis of clusters of unexplained viral respiratory tract infection in Cambodia

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Multiplex PCR analysis of clusters of unexplained viral respiratory tract infection in Cambodia
Creator	Jain, Komal Tokarz, Rafal Sameroff, Stephen Lipkin, Ian Mishra, Nischay Ly, Nary Newell, Steven Rachmat, Agus An, Ung Harrison, Dustin
Source	Medline; PMC
abstract	BACKGROUND: Fevers of unknown origin constitute a substantial disease burden in Southeast Asia. In majority of the cases, the cause of acute febrile illness is not identified. METHODS: We used MassTag PCR, a multiplex assay platform, to test for the presence of 15 viral respiratory agents from 85 patients with unexplained respiratory illness representing six disease clusters that occurred in Cambodia between 2009 and 2012. RESULTS: We detected a virus in 37 (44%) of the cases. Human rhinovirus, the virus detected most frequently, was found in both children and adults. The viruses most frequently detected in children and adults, respectively, were respiratory syncytial virus and enterovirus 68. Sequence analysis indicated that two distinct clades of enterovirus 68 were circulating during this time period. CONCLUSIONS: This is the first report of enterovirus 68 in Cambodia and contributes to the appreciation of this virus as an important respiratory pathogen.
has issue date	2014-12-17(xsd:dateTime)
bibo:doi	10.1186/s12985-014-0224-x
bibo:pmid	25514971
has license	cc-by
sha1sum (hex)	1613fd55dff3cde4f7f32fd5b667e548f860b5d3
schema:url	https://doi.org/10.1186/s12985-014-0224-x
resource representing a document's title	Multiplex PCR analysis of clusters of unexplained viral respiratory tract infection in Cambodia
has PubMed Central identifier	PMC4280028
has PubMed identifier	25514971
schema:publication	Virol J
resource representing a document's body	covid:1613fd55dff3cde4f7f32fd5b667e548f860b5d3#body_text
is schema:about of	named entity 'CLUSTERS' named entity 'substantial' named entity 'febrile' named entity 'BACKGROUND' named entity 'ACUTE FEBRILE ILLNESS' named entity 'NOT IDENTIFIED' named entity 'CASES' named entity 'DISEASE' named entity 'SOUTHEAST ASIA' named entity 'UNKNOWN ORIGIN' named entity 'FEVERS' named entity 'UNEXPLAINED' named entity 'MULTIPLEX PCR' named entity 'MAJORITY' named entity 'VIRAL RESPIRATORY TRACT INFECTION' named entity 'BURDEN' named entity 'CAMBODIA' named entity 'CAUSE' named entity 'PCR ANALYSIS' covid:arg/1613fd55dff3cde4f7f32fd5b667e548f860b5d3 named entity 'cases' named entity 'disease burden' named entity 'Fevers of unknown origin' named entity 'disease burden' named entity 'Cambodia' named entity 'Kandal' named entity 'OC43' named entity 'EV-D68' named entity 'EV-D68' named entity 'dengue' named entity 'cohort study' named entity 'nucleic acid' named entity 'virus' named entity 'z-score' named entity 'HRV' named entity 'antigenic' named entity 'GenBank' named entity 'HRV' named entity 'malaise' named entity 'RSV' named entity 'VP1' named entity 'respiratory disease' named entity 'RSV' named entity 'clinical presentation' named entity 'virus' named entity 'Cambodia' named entity 'EV-D68' named entity 'infection' named entity 'genome' named entity 'virus' named entity 'genome' named entity 'Ratanakiri' named entity 'primer' named entity 'influenza virus' named entity 'EV-D68' named entity 'Institutional Review Board' named entity 'EV-D68' named entity 'viral pathogens' named entity 'Steung Treng' named entity 'headache' named entity 'polymerase chain reaction' named entity 'PCR' named entity 'non-parametric statistics' named entity 'respiratory tract' named entity 'Finland' named entity 'HEV' named entity 'dideoxy sequencing' named entity 'influenza' named entity 'diagnostic assays' named entity 'enterovirus' named entity 'Africa' named entity 'EV-D68'

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