About: Genome Analysis of SARS-CoV-2 Isolate from Bangladesh

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Genome Analysis of SARS-CoV-2 Isolate from Bangladesh
Creator	Ahsan, Giasuddin Hasan, Saam Hossain, Muhammad Khan, Salim
Source	BioRxiv
abstract	Recently the first genome sequence for a Severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 isolate from Bangladesh became available. The sequencing was carried out by the Child Health Research Foundation and provided the first insight into the genetic details of the viral strain responsible for the SARS-CoV-2 infections in Bangladesh. Here we carried out a comparative study were we explored the phylogenetic relationship between the Bangladeshi isolate with other isolates from different parts of the world. Afterwards we identified single nucleotide variants in the Bangladeshi isolate, using the Wuhan virus reference sequence. We found a total of 9 variants in the Bangladeshi isolate using 2 separate tools. Barring 2, the rest of these variants were also observed in other isolates from different countries. Most of the variants occurred in the ORF1ab gen. Another noteworthy finding was a sequence of three consecutive variants in the N protein gene that were observed in other isolates as well. Lastly the phylogenetic analysis revealed a close relationship between the Bangladeshi isolate and those from Taiwan, Kazakhstan, Greece, California, Spain, Israel, and Sri Lanka.
has issue date	2020-05-15(xsd:dateTime)
bibo:doi	10.1101/2020.05.13.094441
has license	biorxiv
sha1sum (hex)	15ee59993a2c9f7edd7c2001e469ae9334319fff
schema:url	https://doi.org/10.1101/2020.05.13.094441
resource representing a document's title	Genome Analysis of SARS-CoV-2 Isolate from Bangladesh
schema:publication	bioRxiv
resource representing a document's body	covid:15ee59993a2c9f7edd7c2001e469ae9334319fff#body_text
is schema:about of	named entity 'Bangladesh' named entity 'infections' named entity 'protein' named entity 'Taiwan' named entity 'phylogenetic' named entity 'SARS-CoV-2' named entity 'N PROTEIN' named entity 'TOOLS' named entity 'Afterwards' named entity 'carried' named entity 'isolate' named entity 'Research' named entity 'Foundation' named entity 'Bangladesh' named entity 'SARS-CoV-2' named entity 'Taiwan' named entity 'viral strain' named entity 'gene' named entity 'reference sequence' named entity 'phylogenetic relationship' named entity 'SARS-CoV-2' named entity 'virus' named entity 'California' named entity 'base pairs' named entity 'pairwise alignment' named entity 'Arizona' named entity 'COVID-19 pandemic' named entity 'protein variants' named entity 'genome' named entity 'Japan' named entity 'South Africa' named entity 'SARS-CoV-2' named entity 'mutation' named entity 'Arizona' named entity 'genome sequence' named entity 'divergence event' named entity 'Arizona' named entity 'Arizona' named entity 'Needleman-Wunsch' named entity 'virus' named entity 'California' named entity 'genetic variants' named entity 'Sri Lanka' named entity 'Spain' named entity 'genome' named entity 'phylogeny' named entity 'virus' named entity 'genetic variants' named entity 'phylogenetic tree' named entity 'virus' named entity 'virus' named entity 'Bangladesh' named entity 'Spike protein' named entity 'genomes' named entity 'NCBI' named entity 'sequenced' named entity 'Spain' named entity 'United States' named entity 'genomes' named entity 'protein' named entity 'SARS-CoV-2' named entity 'MAFFT' named entity 'virus' named entity 'Bangladesh' named entity 'gene' named entity 'virus' named entity 'virus' named entity 'Israel' named entity 'United States' named entity 'genomes' named entity 'heatmap' named entity 'India' named entity 'multiple sequence alignment' named entity 'virus' named entity 'genome' named entity 'gene' named entity 'Maharashtra' named entity 'mutation' named entity 'Italy' named entity 'protein' named entity 'Taiwan'

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