About: Successful rescue of disseminated varicella infection with multiple organ failure in a pediatric living donor liver transplant recipient: a case report and literature review

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About: Successful rescue of disseminated varicella infection with multiple organ failure in a pediatric living donor liver transplant recipient: a case report and literature review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Successful rescue of disseminated varicella infection with multiple organ failure in a pediatric living donor liver transplant recipient: a case report and literature review
Creator	Ihara, Yoshiyuki Mizuta, Koichi Okada, Noriki Sanada, Yukihiro Urahashi, Taizen Wakiya, Taiichi Yamada, Naoya
topic	covid:14638305e09e33a48cacf3dda475da5c600cb40a#this
Source	PMC
abstract	A 12-year-old female patient with biliary atresia underwent living donor liver transplantation (LDLT). Twelve months after the LDLT, she developed acute hepatitis (alanine aminotransferase 584 IU/L) and was diagnosed with disseminated varicella-zoster virus (VZV) infection with high level of serum VZV-DNA (1.5 × 10(5) copies/mL) and generalized vesicular rash. She had received the VZV vaccination when she was 5-years-old and had not been exposed to chicken pox before the LDLT, and her serum was positive for VZV immunoglobulin G at the time of the LDLT. Although she underwent treatment with intravenous acyclovir, intravenous immunoglobulin, and withdrawal of immunosuppressants, her symptoms worsened and were accompanied by disseminated intravascular coagulation, pneumonia, and encephalitis. These complications required treatment in the intensive care unit for 16 days. Five weeks later, her clinical findings improved, although her VZV-DNA levels remained high (8.5 × 10(3)copies/mL). Oral acyclovir was added for 2 weeks, and she was eventually discharged from our hospital on day 86 after admission; she has not experienced a recurrence. In conclusion, although disseminated VZV infection with multiple organ failure after pediatric LDLT is a life-threatening disease, it can be cured via an early diagnosis and intensive treatment.
has issue date	2015-06-17(xsd:dateTime)
bibo:doi	10.1186/s12985-015-0311-7
bibo:pmid	26081644
has license	cc-by
sha1sum (hex)	14638305e09e33a48cacf3dda475da5c600cb40a
schema:url	https://doi.org/10.1186/s12985-015-0311-7
resource representing a document's title	Successful rescue of disseminated varicella infection with multiple organ failure in a pediatric living donor liver transplant recipient: a case report and literature review
has PubMed Central identifier	PMC4480512
has PubMed identifier	26081644
schema:publication	Virol J
resource representing a document's body	covid:14638305e09e33a48cacf3dda475da5c600cb40a#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/14638305e09e33a48cacf3dda475da5c600cb40a
is schema:about of	named entity 'levels' named entity 'VZV' named entity 'generalized' named entity 'multiple organ failure' named entity 'literature review' named entity 'infection' named entity 'AMINOTRANSFERASE' named entity 'COPIES' named entity 'EXPOSED TO' named entity 'BILIARY ATRESIA' named entity 'MONTHS' named entity 'HOSPITAL' named entity 'INTRAVENOUS' named entity 'RECEIVED' named entity '584' named entity 'ENCEPHALITIS' named entity 'DONOR LIVER' named entity 'developed' named entity 'vesicular' named entity 'discharged' named entity 'multiple organ failure' named entity 'encephalitis' named entity 'day' named entity 'intensive care unit' named entity 'infection' named entity 'LDLT' named entity 'multiple organ failure' named entity 'varicella-zoster virus' named entity 'LDLT' named entity 'serum' named entity 'disseminated intravascular coagulation' named entity 'immunosuppressants' named entity 'infection' named entity 'LDLT' named entity 'VZV' named entity 'varicella' named entity 'literature review' named entity 'immunocompromised host' named entity 'VZV' named entity 'alkaline phosphatase' named entity 'prophylactic' named entity 'liver transplantation' named entity 'IgG' named entity 'CPK' named entity 'IgG antibodies' named entity 'PCR' named entity 'MOF' named entity 'pediatric' named entity 'LDLT' named entity 'disseminated intravascular coagulation' named entity 'intensive care unit' named entity 'clinical findings' named entity 'VZV' named entity 'infection' named entity 'vaccination' named entity 'lumbar puncture' named entity 'VZV' named entity 'prophylaxis' named entity 'white blood cell' named entity 'LDLT' named entity 'intravenous' named entity 'intensive treatment' named entity 'herpes viruses' named entity 'steroid' named entity 'LDLT' named entity 'CMV' named entity 'infection' named entity 'mycophenolate mofetil' named entity 'bleeding tendency' named entity 'VZV' named entity 'immunosuppressant' named entity 'follow-up' named entity 'VZV'

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