About: Risk factors for severe acute lower respiratory infections in children

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About: Risk factors for severe acute lower respiratory infections in children – a systematic review and meta-analysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Risk factors for severe acute lower respiratory infections in children – a systematic review and meta-analysis
Creator	Campbell, Harry Nair, Harish Rudan, Igor Falconer, Rachel Jackson, Stewart Mathews, Kyle Pulanić, Dražen
Source	PMC
abstract	AIM: To identify the risk factors in children under five years of age for severe acute lower respiratory infections (ALRI), which are the leading cause of child mortality. METHODS: We performed a systematic review of published literature available in the public domain. We conducted a quality assessment of all eligible studies according to GRADE criteria and performed a meta-analysis to report the odds ratios for all risk factors identified in these studies. RESULTS: We identified 36 studies that investigated 19 risk factors for severe ALRI. Of these, 7 risk factors were significantly associated with severe ALRI in a consistent manner across studies, with the following meta-analysis estimates of odds ratios (with 95% confidence intervals): low birth weight 3.18 (1.02-9.90), lack of exclusive breastfeeding 2.34 (1.42-3.88), crowding – more than 7 persons per household 1.96 (1.53-2.52), exposure to indoor air pollution 1.57 (1.06-2.31), incomplete immunization 1.83 (1.32-2.52), undernutrition – weight-for-age less than 2 standard deviations 4.47 (2.10-9.49), and HIV infection 4.15 (2.57-9.74). CONCLUSION: This study highlights the role of the above seven risk factors in the development of severe pneumonia in under-five children. In addition, it emphasizes the need for further studies investigating other potential risk factors. Since these risk factors are potentially preventable, health policies targeted at reducing their prevalence provide a basis for decreasing the burden of childhood pneumonia.
has issue date	2013-04-01(xsd:dateTime)
bibo:doi	10.3325/cmj.2013.54.110
bibo:pmid	23630139
has license	cc-by
sha1sum (hex)	142a615ffb970d12beaa9597bff2b9c49da4bb96
schema:url	https://doi.org/10.3325/cmj.2013.54.110
resource representing a document's title	Risk factors for severe acute lower respiratory infections in children – a systematic review and meta-analysis
has PubMed Central identifier	PMC3641871
has PubMed identifier	23630139
schema:publication	Croat Med J
resource representing a document's body	covid:142a615ffb970d12beaa9597bff2b9c49da4bb96#body_text
is schema:about of	named entity 'SEVERE' named entity 'ACUTE' covid:arg/142a615ffb970d12beaa9597bff2b9c49da4bb96 named entity 'AGE' named entity 'RISK FACTORS' named entity 'AIM' named entity 'ACUTE' named entity 'SYSTEMATIC REVIEW' named entity 'CHILDREN' named entity 'RESPIRATORY INFECTIONS' named entity 'CHILDREN' named entity 'META-ANALYSIS' named entity 'OF CHILD' named entity 'LEADING' named entity 'RISK FACTORS' named entity 'LOWER' named entity 'TO IDENTIFY' named entity 'CAUSE' named entity 'LOWER' named entity 'RESPIRATORY INFECTIONS' named entity 'SEVERE' named entity 'YEARS' named entity 'CHILD MORTALITY' named entity 'child mortality' named entity 'ALRI' named entity 'meta-analysis' named entity 'lower respiratory infections' named entity 'systematic review' named entity 'Risk factors' named entity 'Aim' named entity 'rickets' named entity 'odds ratio' named entity 'risk factors' named entity 'odds ratio' named entity 'low-birth-weight' named entity 'HIV' named entity 'immunization' named entity 'hemoglobin' named entity 'odds ratio' named entity 'immunization' named entity 'burden of disease' named entity 'pneumonia' named entity 'preterm births' named entity 'undernutrition' named entity 'odds ratio' named entity 'smokers' named entity 'risk factors' named entity 'young children' named entity 'risk factors' named entity 'Haemophilus influenzae' named entity 'developing countries' named entity '1.6' named entity 'odds ratio' named entity 'risk factors' named entity 'ALRI' named entity 'ALRI' named entity 'health policies' named entity 'ALRI' named entity '1.1' named entity '95% CI' named entity 'ALRI' named entity 'risk factor' named entity 'ALRI' named entity 'odds ratio' named entity 'odds ratios' named entity 'confidence intervals' named entity 'severe pneumonia' named entity 'ALRI' named entity 'ethical approval' named entity '2.2' named entity 'ALRI' named entity 'ALRI' named entity 'immunization' named entity 'Anemia' named entity 'study designs'

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