About: Identification and complete genome analysis of three novel paramyxoviruses, Tuhoko virus 1, 2 and 3, in fruit bats from China

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About: Identification and complete genome analysis of three novel paramyxoviruses, Tuhoko virus 1, 2 and 3, in fruit bats from China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Identification and complete genome analysis of three novel paramyxoviruses, Tuhoko virus 1, 2 and 3, in fruit bats from China
Creator	Zheng, Bo-Jian Yuen, Kwok-Yung Wang, Ming Chan, Kwok-Hung Guo, Rongtong Lee, Paul Tsoi, Hoi-Wah Xu, Huifang Lau, Susanna Li, Kenneth Poon, Rosana Wong, Annette Wong, Beatrice Woo, Patrick
Source	Elsevier; Medline; PMC
abstract	Abstract Among 489 bats of 11 species in China, three novel paramyxoviruses [Tuhokovirus 1, 2 and 3 (ThkPV-1, ThkPV-2 and ThkPV-3)] were discovered in 15 Leschenault's rousettes. Phylogenetically, the three viruses are most closely related to Menangle and Tioman virus. Genome analysis showed that their 3'-leader sequences are unique by possessing GA instead of AG at the 5th and 6th positions. Unlike Menangle and Tioman virus, key amino acids for neuraminidase activity characteristic of rubulavirus attachment proteins are present. The genome of ThkPV-1 represents the largest rubulavirus genome. Unique features between the three viruses include perfect complementary 5'-trailer and 3'-leader sequence and a unique cysteine pair in attachment protein of ThkPV-1, G at +1 position in all predicted mRNA sequences of ThkPV-2, and amino acid substitutions in the conserved N-terminal motif of nucleocapsid of ThkPV-3. Analysis of phosphoprotein gene mRNA products confirmed mRNA editing. Antibodies to the viruses were detected in 48–60% of Leschenault's rousettes.
has issue date	2010-08-15(xsd:dateTime)
bibo:doi	10.1016/j.virol.2010.03.049
bibo:pmid	20537670
has license	els-covid
sha1sum (hex)	13ecb811532b9ddd1f13ef2a2a6c2441b8a49f44
schema:url	https://doi.org/10.1016/j.virol.2010.03.049
resource representing a document's title	Identification and complete genome analysis of three novel paramyxoviruses, Tuhoko virus 1, 2 and 3, in fruit bats from China
has PubMed Central identifier	PMC7111929
has PubMed identifier	20537670
schema:publication	Virology
resource representing a document's body	covid:13ecb811532b9ddd1f13ef2a2a6c2441b8a49f44#body_text
is schema:about of	named entity 'mRNA' named entity 'conserved' named entity 'rubulavirus' named entity 'paramyxoviruses' named entity 'genome' named entity 'VIRUS' named entity 'INCLUDE' named entity '27S' named entity 'BATS' named entity 'RELATED' named entity 'PARAMYXOVIRUSES' named entity 'PHOSPHOPROTEIN' named entity 'THEIR' named entity 'VIRUS' named entity 'PROTEINS' named entity 'UNIQUE' named entity 'RUBULAVIRUS' named entity 'GENOME' named entity 'TRAILER' named entity '5TH' named entity 'CYSTEINE' named entity 'SEQUENCES' named entity 'GENE' named entity 'POSITION' named entity 'PRESENT' named entity 'FEATURES' named entity 'POSITIONS' named entity 'MRNA' named entity 'NUCLEOCAPSID' named entity 'CHINA' named entity 'PROTEIN ' named entity 'ANTIBODIES' named entity 'AMINO ACIDS' named entity '2B1' named entity 'NOVEL' named entity 'COMPLETE' named entity 'CONSERVED' named entity 'CHARACTERISTIC' named entity 'PAIR' named entity 'VIRUSES' named entity 'LARGEST' named entity 'PREDICTED' named entity '6TH' named entity '60%' named entity 'FRUIT BATS' named entity 'CHINA' named entity 'GENOME ANALYSIS' named entity 'IDENTIFICATION' named entity 'NOVEL' named entity 'AMINO ACID SUBSTITUTIONS' named entity 'PRODUCTS' named entity 'GENOME ANALYSIS' named entity 'CONFIRMED' named entity 'ANALYSIS' named entity 'MOTIF' named entity 'MRNA EDITING' named entity 'ATTACHMENT' named entity 'DETECTED' named entity 'KEY' named entity 'LEADER SEQUENCE' named entity 'SPECIES' named entity 'NEURAMINIDASE ACTIVITY' named entity 'PARAMYXOVIRUSES' named entity 'unique' named entity 'viruses' named entity 'key' named entity 'predicted' named entity 'attachment'

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