About: Causes of Death and Comorbidities in Patients with COVID-19

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Causes of Death and Comorbidities in Patients with COVID-19
Creator	Corman, Victor Bischoff, Philip Elezkurtaj, Sefer Gerhold, Manuela Greuel, Selina Hauptmann, Kathrin Heppner, Frank Herbst, Hermann Horst, David Ihlow, Jana Ingold-Heppner, Barbara Kunze, Catarina Martin, Hubert Michaelis, Edward Miller, Florian Radbruch, Helena Sinn, Bruno
Source	MedRxiv
abstract	Infection by the new corona virus strain SARS-CoV-2 and its related syndrome COVID-19 has caused several hundreds of thousands of deaths worldwide. Patients of higher age and with preexisting chronic health conditions are at an increased risk of fatal disease outcome. However, detailed information on causes of death and the contribution of comorbidities to death yet is missing. Here, we report autopsy findings on causes of death and comorbidities of 26 decedents that had clinically presented with severe COVID-19. We found that septic shock and multi organ failure was the most common immediate cause of death, often due to suppurative pulmonary infection. Respiratory failure due to diffuse alveolar damage presented as the most immediate cause of death in fewer cases. Several comorbidities, such as hypertension, ischemic heart disease, and obesity were present in the vast majority of patients. Our findings reveal that causes of death were directly related to COVID-19 in the majority of decedents, while they appear not to be an immediate result of preexisting health conditions and comorbidities. We therefore suggest that the majority of patients had died of COVID-19 with only contributory implications of preexisting health conditions to the mechanism of death.
has issue date	2020-06-17(xsd:dateTime)
bibo:doi	10.1101/2020.06.15.20131540
has license	medrxiv
sha1sum (hex)	130c18b70c5617aa352b88e3908346eab6831144
schema:url	https://doi.org/10.1101/2020.06.15.20131540
resource representing a document's title	Causes of Death and Comorbidities in Patients with COVID-19
resource representing a document's body	covid:130c18b70c5617aa352b88e3908346eab6831144#body_text
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