About: Initial events in the pathogenesis of acute tonsillitis caused by Streptococcus pyogenes 1 This paper was presented in part at the XVI World Congress of Otorhinolaryngology, Head and Neck Surgery, Sydney, Australia, March 2

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About: Initial events in the pathogenesis of acute tonsillitis caused by Streptococcus pyogenes 1 This paper was presented in part at the XVI World Congress of Otorhinolaryngology, Head and Neck Surgery, Sydney, Australia, March 2–7, 1997. 1 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Initial events in the pathogenesis of acute tonsillitis caused by Streptococcus pyogenes 1 This paper was presented in part at the XVI World Congress of Otorhinolaryngology, Head and Neck Surgery, Sydney, Australia, March 2–7, 1997. 1
Creator	Lilja, Markus Räisänen, Simo Stenfors, Lars-Eric
Source	Elsevier; Medline; PMC
abstract	Abstract Bacterial and epithelial cell samples were obtained, within 24 h of onset of pharyngeal symptoms, from the palatine tonsils of nine patients (four female and five male; age range 10–40 years, median age 23) with acute tonsillitis, culture-positive for Streptococcus pyogenes. The specimens were examined using fluorescein isothiocyanate- (FITC) and gold-labelled antiserum to S. pyogenes and fluorescence, scanning electron and transmission electron microscopy. S. pyogenes could be identified both in the mucous layer covering the tonsils and attached to the surface epithelial cells. Long chains of coccus-shaped bacteria could be seen encroaching on the epithelial cell borders. S. pyogenes can apparently penetrate the mucous barrier, attach to the epithelial cells, spread from cell to cell and possibly penetrate into the outermost layer of the epithelial cells. These events in turn provoke cytokine production and/or complement activation, which induce inflammatory reaction in the tonsillar tissue.
has issue date	1998-09-15(xsd:dateTime)
bibo:doi	10.1016/s0165-5876(98)00071-8
bibo:pmid	9804015
has license	els-covid
sha1sum (hex)	119a2f1357346c9a9b83d328b28a1c61e000c2b8
schema:url	https://doi.org/10.1016/s0165-5876%2898%2900071-8
resource representing a document's title	Initial events in the pathogenesis of acute tonsillitis caused by Streptococcus pyogenes 1 This paper was presented in part at the XVI World Congress of Otorhinolaryngology, Head and Neck Surgery, Sydney, Australia, March 2–7, 1997. 1
has PubMed Central identifier	PMC7173150
has PubMed identifier	9804015
schema:publication	International Journal of Pediatric Otorhinolaryngology
resource representing a document's body	covid:119a2f1357346c9a9b83d328b28a1c61e000c2b8#body_text
is schema:about of	named entity 'Bacterial' named entity 'epithelial cell' named entity 'complement activation' named entity 'age' named entity 'layer' named entity 'pathogenesis' named entity 'CHAINS' named entity 'SEEN' named entity 'BORDERS' named entity 'These' named entity 'tissue' named entity 'antiserum' named entity 'S. pyogenes' named entity 'median age' named entity 'male' named entity 'epithelial cells' named entity 'turn' named entity 'cytokine' named entity 'chains' named entity 'induce' named entity 'S. pyogenes' named entity 'pharyngeal' named entity 'palatine tonsils' named entity 'epithelial cell' named entity 'antiserum' named entity 'epithelial cells' named entity 'tonsils' named entity 'S. pyogenes' named entity 'surface epithelial' named entity 'epithelial cells' named entity 'epithelium' named entity 'FITC' named entity 'tonsillar' named entity 'complement activation' named entity 'glutaraldehyde' named entity 'Lipoteichoic acid' named entity 'microorganisms' named entity 'FITC' named entity 'S. mitis' named entity 'epithelial cells' named entity 'S. pyogenes' named entity 'supernatant' named entity 'Neisseria sicca' named entity 'Viruses' named entity 'coccus-shaped' named entity 'Streptococcus' named entity 'physiological' named entity 'pathogenic microorganisms' named entity 'centrifugated' named entity 'epithelial cells' named entity 'JEOL' named entity 'alcohol' named entity 'antiserum' named entity 'bacterial pathogens' named entity 'microorganisms' named entity 'pathogens' named entity 'Pharmacia' named entity 'acute tonsillitis' named entity 'cytokine' named entity 'S. pyogenes' named entity 'methyl cellulose' named entity 'infection' named entity 'infection' named entity 'physiological' named entity 'diamond knives' named entity 'inflammatory reaction' named entity 'pharyngeal' named entity 'GABHS' named entity 'coxsackie' named entity 'serum' named entity 'fluorescence' named entity 'infection' named entity 'acute tonsillitis' named entity 'coccal' named entity 'phagocytosis' named entity 'antiserum' named entity 'herpes simplex' named entity 'tonsillar' named entity 'antibiotics'

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