About: Evaluation of bacteriophage efficacy in reducing the impact of single and mixed infections with Escherichia coli and infectious bronchitis in chickens

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About: Evaluation of bacteriophage efficacy in reducing the impact of single and mixed infections with Escherichia coli and infectious bronchitis in chickens Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Evaluation of bacteriophage efficacy in reducing the impact of single and mixed infections with Escherichia coli and infectious bronchitis in chickens
Creator	Samy, Ahmed Nabil, Nehal Tawakol, Maram
source	Medline; PMC
abstract	Infectious bronchitis virus (IBV) represents a major threat to poultry production worldwide particularly when complicated with bacterial infection. In the present study samples were collected from forty broiler farms with respiratory manifestations to characterize IBV and E. coli. Bacteriophages were isolated and enriched from sampled farms to study its efficacy to control single and mixed infections with E. coli and IBV in vivo. Twelve out of forty farms were positive for IBV. Phylogenetic analysis of partial spike protein revealed that all positive cases clustered within the GI-23 genotype. Eight out of forty farms were positive for E. coli serogroups O26, O78, O86, O114, O119, with O125 found on three farms. Bacteriophage treatment delayed the onset and reduced the severity of clinical signs, and prevented the mortality associated with single and mixed infection with IBV and E. coli. Furthermore, in mixed infections, bacteriophage treatment significantly reduced E. coli as well as IBV shedding. Groups treated with bacteriophages showed a significant reduction of E. coli shedding that gradually decreased over time, in contrast to higher and gradually increasing shedding without bacteriophage treatment. In conclusion, bacteriophage treatment significantly reduced the pathogenicity and shedding of IBVand E. coli in mixed infections.
has issue date	2019-11-29(xsd:dateTime)
bibo:doi	10.1080/20008686.2019.1686822
bibo:pmid	31839902
has license	cc-by
sha1sum (hex)	11914635e8fc7c041e815263d5e20ca4ad9166bb
schema:url	https://doi.org/10.1080/20008686.2019.1686822
resource representing a document's title	Evaluation of bacteriophage efficacy in reducing the impact of single and mixed infections with Escherichia coli and infectious bronchitis in chickens
has PubMed Central identifier	PMC6896464
has PubMed identifier	31839902
schema:publication	Infect Ecol Epidemiol
resource representing a document's body	covid:11914635e8fc7c041e815263d5e20ca4ad9166bb#body_text
is schema:about of	named entity 'infection' named entity 'Phylogenetic analysis' named entity 'protein' named entity 'forty' named entity 'sampled' named entity 'farms' named entity 'chickens' named entity 'Evaluation' named entity 'EVALUATION' named entity 'COLLECTED' covid:arg/11914635e8fc7c041e815263d5e20ca4ad9166bb named entity 'SINGLE' named entity 'INFECTIOUS BRONCHITIS' named entity 'TREATMENT' named entity 'IN VIVO' named entity 'DELAYED' named entity 'BACTERIAL INFECTION' named entity 'INFECTIOUS BRONCHITIS VIRUS' named entity 'BROILER' named entity 'SPIKE PROTEIN' named entity 'TO CHARACTERIZE' named entity 'MIXED' named entity 'CLINICAL SIGNS' named entity 'MANIFESTATIONS' named entity 'CASES' named entity 'INFECTIONS' named entity 'EFFICACY' named entity 'ONSET' named entity 'EFFICACY' named entity 'MIXED' named entity 'IMPACT' named entity 'BACTERIOPHAGE' named entity 'SINGLE' named entity 'MIXED INFECTION' named entity 'ASSOCIATED WITH' named entity 'BACTERIOPHAGES' named entity 'A MAJOR' named entity 'ITS' named entity 'FORTY' named entity 'POSITIVE FOR' named entity 'TO CONTROL' named entity 'THREAT' named entity 'PATHOGENICITY' named entity 'REDUCED' named entity 'E. COLI' named entity 'REDUCTION' named entity 'CLUSTERED' named entity 'PROTEIN ' named entity 'SIGNIFICANT' named entity 'SAMPLES' named entity 'WORLDWIDE' named entity 'GENOTYPE' named entity 'INFECTIONS' named entity 'HIGHER' named entity 'DECREASED' named entity 'REVEALED' named entity 'ISOLATED' named entity 'PRESENT' named entity 'POSITIVE' named entity 'POULTRY PRODUCTION' named entity 'PHYLOGENETIC ANALYSIS' named entity 'O86' named entity 'TREATED WITH' named entity 'SEVERITY' named entity 'GROUPS' named entity 'MORTALITY' named entity 'PARTIAL' named entity 'REDUCING' named entity 'SHEDDING' named entity 'COMPLICATED' named entity 'TIME' named entity 'SAMPLED' named entity 'CONCLUSION' named entity 'RESPIRATORY' named entity 'STUDY' named entity 'SEROGROUPS' named entity 'INCREASING' named entity 'ENRICHED' named entity 'CHICKENS'

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