About: Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus
Creator	Erlandson, Karl Donabedian, Armen Hojvat, Sally Hu-Primmer, Jean Korch, George Wathen, Michael Uyeki, Timothy Stemmy, Erik Donabedian, A Erlandson, K Hu-Primmer, J Korch, G O'hara, M O'hara, Michael Wathen, M
Source	Medline; PMC
abstract	Preclinical development of and research on potential Middle East respiratory syndrome coronavirus (MERS-CoV) medical countermeasures remain preliminary; advancements are needed before most countermeasures are ready to be tested in human clinical trials. Research priorities include standardization of animal models and virus stocks for studying disease pathogenesis and efficacy of medical countermeasures; development of MERS-CoV diagnostics; improved access to nonhuman primates to support preclinical research; studies to better understand and control MERS-CoV disease, including vaccination studies in camels; and development of a standardized clinical trial protocol. Partnering with clinical trial networks in affected countries to evaluate safety and efficacy of investigational therapeutics will strengthen efforts to identify successful medical countermeasures.
has issue date	2016-07-01(xsd:dateTime)
bibo:doi	10.3201/eid2207.160022
bibo:pmid	27191188
has license	no-cc
sha1sum (hex)	0f82974698355743046b60766dc767f02c357ad0
schema:url	https://doi.org/10.3201/eid2207.160022
resource representing a document's title	Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus
has PubMed Central identifier	PMC4918159
has PubMed identifier	27191188
schema:publication	Emerg Infect Dis
resource representing a document's body	covid:0f82974698355743046b60766dc767f02c357ad0#body_text
is schema:about of	named entity 'preclinical' named entity 'studying' named entity 'disease' named entity 'vaccination' named entity 'DEVELOPMENT' named entity 'CLINICAL TRIALS' named entity 'UNDERSTAND' named entity 'THERAPEUTICS' named entity 'CAMELS' named entity 'VIRUS' named entity 'BETTER' named entity 'INVESTIGATIONAL' named entity 'RESEARCH PRIORITIES' named entity 'TO IDENTIFY' named entity 'NETWORKS' named entity 'ANIMAL MODELS ' covid:arg/0f82974698355743046b60766dc767f02c357ad0 named entity 'DISEASE' named entity 'HUMAN' named entity 'TO SUPPORT' named entity 'MEDICAL COUNTERMEASURES' named entity 'TESTED' named entity 'INCLUDING' named entity 'EVALUATE' named entity 'PATHOGENESIS' named entity 'CLINICAL TRIAL PROTOCOL' named entity 'CONTROL' named entity 'POTENTIAL' named entity 'PRECLINICAL' named entity 'AFFECTED' named entity 'DIAGNOSTICS' named entity 'ACCESS' named entity 'PRELIMINARY' named entity 'MEDICAL COUNTERMEASURES' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'ONLINE' named entity 'REPORT' named entity 'NONHUMAN PRIMATES' named entity 'INCLUDE' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'RESEARCH' named entity 'STUDIES' named entity 'DEVELOPMENT' named entity 'VACCINATION' named entity 'IMPROVED' named entity 'COUNTRIES' named entity 'NEEDED' named entity 'CLINICAL TRIAL' named entity 'SUCCESSFUL' named entity 'EFFICACY' named entity 'SAFETY' named entity 'STANDARDIZATION' named entity 'ready' named entity 'European Medicines Agency' named entity 'healthcare personnel' named entity 'MERS-CoV' named entity 'immunomodulators' named entity 'postexposure prophylaxis' named entity 'spike protein' named entity 'infection' named entity 'MERS-CoV' named entity 'clinical trial' named entity 'countermeasures' named entity 'MERS-CoV' named entity 'animal models' named entity 'medical countermeasures' named entity 'vaccination'

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