About: Has India met this enemy before? From an eternal optimist’s perspective: SARS-CoV-2

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About: Has India met this enemy before? From an eternal optimist’s perspective: SARS-CoV-2 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Has India met this enemy before? From an eternal optimist’s perspective: SARS-CoV-2
Creator	Kulkarni, Padmaj Kumar, Rohit Aggarwal, Shyam Bahl, Charu Batra, Atul Mehta, Prashant Pabbi, Swati Parikh, Purvish Patel, Amol Sahoo, Ranjit Sharma, Ajendra Govinda Gupta, Vineet
Source	PMC
abstract	OBJECTIVE: We are presently going through a historic and unprecedented crisis for humanity with SARS-CoV-2 causing immense damage to life and world economics. It has been 3 months, since we had the first cluster in China and we felt the need to look into certain regional patterns of transmission of the virus with respect to some distinctive living conditions, incidence of malaria, the genomics of different strains, and its impact on severity. MATERIAL AND METHODS: Data for 107 countries was compiled and correlation analysis was done between incidence of malaria and number of SARS-CoV-2 cases. Possibility of genetic similarity between SARS-CoV-2 and reported zoonotic RNA viruses found associated previously with some Plasmodium species was explored by utilizing NCBI database. RESULTS: We found a significant inverse correlation between SARS-CoV-2 disease burden and incidence of Malaria. Our analysis also showed that a 12 base pair region encoding a part of surface glycoprotein of SARS- CoV-2 aligned with the Plasmodium associated zoonotic viral genome. CONCLUSION: Our analysis suggests a significantly lower SARS-CoV-2 disease burden in Malaria endemic regions and an inverse correlation with incidence of Malaria. The possibility of a pre-existing immunological memory for SARS-CoV-2 in Indians is possible and needs to be explored further
has issue date	2020-04-30(xsd:dateTime)
bibo:doi	10.25259/ijms_30_2020
has license	cc-by-nc-sa
sha1sum (hex)	0b0989e8df039c658e71f0e692a112d6f7aa64e2
schema:url	https://doi.org/10.25259/ijms_30_2020
resource representing a document's title	Has India met this enemy before? From an eternal optimist’s perspective: SARS-CoV-2
has PubMed Central identifier	PMC7217268
schema:publication	Indian J Med Sci
resource representing a document's body	covid:0b0989e8df039c658e71f0e692a112d6f7aa64e2#body_text
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