About: Responsible Translational Pathways for Germline Gene Editing?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Responsible Translational Pathways for Germline Gene Editing?
Creator	Editors, Chan, Section Genome Editing, (y Fan & J
Source	Medline; PMC
abstract	PURPOSE OF REVIEW: Continued development of gene editing techniques has raised the real possibility of clinical application of germline gene editing. These results, as well as reports of an unethical experiment which resulted in the birth of at least two children from edited embryos in 2018, have highlighted the urgency and importance of ethical issues about translational pathways for editing of human germline cells. Charting responsible translational pathways for germline gene editing requires tackling some significant and complex ethical issues. RECENT FINDINGS: A literature on development of clinical applications of germline gene editing is emerging, and several key ethical issues are coming into focus as major challenges for responsible translational pathways. SUMMARY: Potential clinical utility, clinical justification, and human subjects research for germline gene editing raise outstanding ethical questions. Work on these questions will help provide guidance to researchers and clinicians and direct translational projects toward justifiable applications.
has issue date	2020-08-21(xsd:dateTime)
bibo:doi	10.1007/s40778-020-00179-x
bibo:pmid	32844082
has license	no-cc
sha1sum (hex)	0aab961b3794295f758a460d632b0d322f733c9f
schema:url	https://doi.org/10.1007/s40778-020-00179-x
resource representing a document's title	Responsible Translational Pathways for Germline Gene Editing?
has PubMed Central identifier	PMC7441015
has PubMed identifier	32844082
schema:publication	Curr Stem Cell Rep
resource representing a document's body	covid:0aab961b3794295f758a460d632b0d322f733c9f#body_text
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