About: Baseline characteristics and risk factors for short-term outcomes in 132 COVID-19 patients with diabetes in Wuhan China: a retrospective study

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About: Baseline characteristics and risk factors for short-term outcomes in 132 COVID-19 patients with diabetes in Wuhan China: a retrospective study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Baseline characteristics and risk factors for short-term outcomes in 132 COVID-19 patients with diabetes in Wuhan China: a retrospective study
Creator	Liu, Jia Wang, Lixia Li, Yumin Wang, L Cao, Y Fan, Yanqing Han, Xiaoyu Shi, Heshui Li, Y Alwalid, Osamah Cao, Yukun Gu, Jin Liu, J Shi, H Fan, Y Gu, J Alwalid, O Cui, Y Cui, Yue Han, X
Source	Elsevier; Medline; PMC
abstract	Abstract Aims To investigate the clinical characteristics, laboratory findings and high- resolution CT (HRCT) features and to explore the risk factors for in-hospital death and complications of coronavirus disease 2019 (COVID-19) patients with diabetes. Methods From Dec 31, 2019, to Apr 5, 2020, a total of 132 laboratory-confirmed COVID-19 patients with diabetes from two hospitals were retrospectively included in our study. Clinical, laboratory and chest CT data were analyzed and compared between the two groups with an admission glucose level of ≤11mmol/L (group 1) and >11mmol/L (group 2). Logistic regression analyses were used to identify the risk factors associated with in-hospital death and complications. Results Of 132 patients, 15 died in hospital and 113 were discharged. Patients in group 2 were more likely to require intensive care unit care (21.4% vs. 9.2%), to develop acute respiratory distress syndrome (ARDS) (23.2% vs. 9.25%) and acute cardiac injury (12.5% vs. 1.3%), and had a higher death rate (19.6% vs. 5.3%) than group 1. In the multivariable analysis, patients with admission glucose of >11 mmol/l had an increased risk of death (OR: 7.629, 95%CI: 1.391-37.984) and in-hospital complications (OR: 3.232, 95%CI: 1.393-7.498). Admission d-dimer of ≥1.5 μg/mL (OR: 6.645, 95%CI: 1.212-36.444) and HRCT score of ≥10 (OR: 7.792, 95%CI: 2.195-28.958) were associated with increased odds of in-hospital death and complications, respectively. Conclusions In COVID-19 patients with diabetes, poorly-controlled blood glucose (>11mmol/L) may be associated with poor outcomes. Admission hyperglycemia, elevated d-dimer and high HRCT score are potential risk factors for adverse outcomes and death.
has issue date	2020-07-03(xsd:dateTime)
bibo:doi	10.1016/j.diabres.2020.108299
bibo:pmid	32623030
has license	els-covid
sha1sum (hex)	0770d41b4d73d1e9eb65f0ad3519cee9180e3467
schema:url	https://doi.org/10.1016/j.diabres.2020.108299
resource representing a document's title	Baseline characteristics and risk factors for short-term outcomes in 132 COVID-19 patients with diabetes in Wuhan China: a retrospective study
has PubMed Central identifier	PMC7332424
has PubMed identifier	32623030
schema:publication	Diabetes Res Clin Pract
resource representing a document's body	covid:0770d41b4d73d1e9eb65f0ad3519cee9180e3467#body_text
is schema:about of	named entity 'COVID-19' named entity 'glucose' named entity 'glucose level' named entity 'blood glucose' named entity 'organ' named entity 'retrospective study' named entity 'diabetes' named entity 'diabetes' named entity 'd-dimer' named entity 'retrospective study' named entity 'CT images' named entity 'absolute lymphocyte count' named entity 'SARS-CoV-2' named entity 'risk of death' named entity 'risk factor' named entity 'statistically significant' named entity 'SARS-CoV-2' named entity 'China' named entity 'WHO' named entity 'antibiotic treatments' named entity 'radiologists' named entity 'ground glass opacity' named entity 'endothelial function' named entity 'type 2 diabetic patients' named entity 'SARS-CoV' named entity 'diabetes' named entity 'thrombus' named entity 'lung lobe' named entity 'COVID' named entity 'ACE2' named entity 'atherosclerosis' named entity 'respiratory support' named entity 'myoglobin' named entity 'diabetes' named entity 'risk factor' named entity '14.5' named entity 'prognosis' named entity 'shortness of breath' named entity 'general population' named entity 'chest CT' named entity 'medical records' named entity 'comorbidities' named entity 'FBG' named entity 'oxygen saturation' named entity 'COVID-19' named entity 'risk factors' named entity 'laboratory test' named entity 'albumin' named entity 'glucose' named entity 'Hubei' named entity 'diabetes' named entity 'FBG' named entity 'plasma glucose' named entity 'risk factors' named entity 'risk factors' named entity 'troponin' named entity 'thoracic' named entity 'symptom' named entity 'prognosis' named entity 'fever' named entity 'ARDS' named entity 'Severe Acute Respiratory Syndrome coronavirus'

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