About: Computational Analysis of Cysteine Proteases (Clan CA, Family C1) of Leishmania major to Find Potential Epitopic Regions

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About: Computational Analysis of Cysteine Proteases (Clan CA, Family C1) of Leishmania major to Find Potential Epitopic Regions Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Computational Analysis of Cysteine Proteases (Clan CA, Family C1) of Leishmania major to Find Potential Epitopic Regions
Creator	Mohabatkar, Hassan Saffari, Babak
Source	PMC
abstract	Leishmania is associated with a broad spectrum of diseases, ranging from simple cutaneous to invasive visceral leishmaniasis. Here, the sequences of ten cysteine proteases of types A, B and C of Leishmania major were obtained from GeneDB database. Prediction of MHC class I epitopes of these cysteine proteases was performed by NetCTL program version 1.2. In addition, by using BcePred server, different structural properties of the proteins were predicted to find out their potential B cell epitopes. According to this computational analysis, nine regions were predicted as B cell epitopes. The results provide useful information for designing peptide-based vaccines.
has issue date	2009-11-25(xsd:dateTime)
bibo:doi	10.1016/s1672-0229(08)60037-6
bibo:pmid	19944381
has license	cc-by-nc-sa
sha1sum (hex)	06c4f9daabdf5ee16fb4b581a954e3909d9f17a0
schema:url	https://doi.org/10.1016/s1672-0229%2808%2960037-6
resource representing a document's title	Computational Analysis of Cysteine Proteases (Clan CA, Family C1) of Leishmania major to Find Potential Epitopic Regions
has PubMed Central identifier	PMC5054412
has PubMed identifier	19944381
schema:publication	Genomics Proteomics Bioinformatics
resource representing a document's body	covid:06c4f9daabdf5ee16fb4b581a954e3909d9f17a0#body_text
is schema:about of	named entity 'B CELL' named entity 'VISCERAL LEISHMANIASIS' named entity 'ACCORDING' named entity 'USEFUL INFORMATION' named entity 'VACCINES' named entity 'SIMPLE' named entity 'GENEDB' named entity 'DIF' named entity 'STRUCTURAL' named entity 'REGIONS' named entity 'TYPES' named entity 'PROVIDE' named entity 'PROTEINS' named entity 'POTENTIAL' named entity 'CYSTEINE PROTEASES' named entity 'B cell' named entity 'ranging' named entity 'BROAD SPECTRUM' named entity 'OBTAINED' named entity 'INVASIVE' named entity 'LEISHMANIA' named entity 'SERVER' named entity 'COMPUTATIONAL ANALYSIS' named entity 'LEISHMANIA MAJOR' named entity 'POTENTIAL' named entity 'CYSTEINE PROTEASES' named entity 'EPITOPIC' named entity 'THESE' named entity 'DATABASE' named entity 'PROPERTIES' named entity 'PERFORMED BY' named entity 'MHC CLASS I' named entity 'PEPTIDE' named entity 'LEISHMANIA MAJOR' named entity 'IND' named entity '1.2' named entity 'PREDICTED' named entity 'RESULTS' named entity 'REGIONS' named entity 'PROGRAM' named entity 'HERE' named entity 'USING' named entity 'PREDICTION' named entity 'COMPUTATIONAL ANALYSIS' named entity 'FAMILY' named entity 'ADDITION' named entity 'BASED' named entity 'SEQUENCES' named entity 'DISEASES' named entity 'CUTANEOUS' named entity 'EPITOPES' named entity 'ASSOCIATED WITH' named entity 'THEIR' named entity 'VERSION' covid:arg/06c4f9daabdf5ee16fb4b581a954e3909d9f17a0 named entity 'dif' named entity 'ten' named entity 'program' named entity 'computational' named entity 'version' named entity 'provide' named entity 'Potential' named entity 'spectrum of diseases' named entity 'vaccines' named entity '1.2' named entity 'epitopes' named entity 'Leishmania' named entity 'Cysteine Proteases' named entity 'bioinformatics' named entity 'locus' named entity 'HLA loci' named entity 'L. major' named entity 'artificial neural networks' named entity 'HLA' named entity 'pathogens' named entity 'Amastigotes' named entity 'signal peptide' named entity 'amino acid sequence' named entity 'epitopic' named entity 'alleles'

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