About: Prone positioning monitored by electrical impedance tomography in patients with severe acute respiratory distress syndrome on veno-venous ECMO

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Prone positioning monitored by electrical impedance tomography in patients with severe acute respiratory distress syndrome on veno-venous ECMO Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Prone positioning monitored by electrical impedance tomography in patients with severe acute respiratory distress syndrome on veno-venous ECMO
Creator	Combes, Alain Nieszkowska, Ania Schmidt, Matthieu Luyt, Charles-Edouard Bréchot, Nicolas Lebreton, Guillaume Hekimian, Guillaume Le Guennec, Loïc Bourcier, Simon Demondion, Pierre Franchineau, Guillaume
Source	PMC
abstract	BACKGROUND: Prone positioning (PP) during veno-venous ECMO is feasible, but its physiological effects have never been thoroughly evaluated. Our objectives were to describe, through electrical impedance tomography (EIT), the impact of PP on global and regional ventilation, and optimal PEEP level. METHODS: A monocentric study conducted on ECMO-supported severe ARDS patients, ventilated in pressure-controlled mode, with 14-cmH(2)O driving pressure and EIT-based “optimal PEEP”. Before, during and after a 16-h PP session, EIT-based distribution and variation of tidal impedance, VT(dorsal)/VT(global) ratio, end-expiratory lung impedance (EELI) and static compliance were collected. Subgroup analyses were performed in patients who increased their static compliance by ≥ 3 mL/cmH(2)O after 16 h of PP. RESULTS: For all patients (n = 21), tidal volume and EELI were redistributed from ventral to dorsal regions during PP. EIT-based optimal PEEP was significantly lower in PP than in supine position. Median (IQR) optimal PEEP decreased from 14 (12–16) to 10 (8–14) cmH(2)O. Thirteen (62%) patients increased their static compliance by ≥ 3 mL/cmH(2)O after PP on ECMO. This subgroup had higher body mass index, more frequent viral pneumonia, shorter ECMO duration, and lower baseline VT(dorsal)/VT(global) ratio than patients with compliance ≤ 3 mL/cmH(2)O (P < 0.01). CONCLUSION: Although baseline tidal volume distribution on EIT may predict static compliance improvement after PP on ECMO, our results support physiological benefits of PP in all ECMO patients, by modifying lung mechanics and potentially reducing VILI. Further studies, including a randomized–controlled trial, are now warranted to confirm potential PP benefits during ECMO.
has issue date	2020-02-03(xsd:dateTime)
bibo:doi	10.1186/s13613-020-0633-5
bibo:pmid	32016593
has license	cc-by
sha1sum (hex)	0678ab3b16576deda330bf2472abda14e867eace
schema:url	https://doi.org/10.1186/s13613-020-0633-5
resource representing a document's title	Prone positioning monitored by electrical impedance tomography in patients with severe acute respiratory distress syndrome on veno-venous ECMO
has PubMed Central identifier	PMC6997307
has PubMed identifier	32016593
schema:publication	Ann Intensive Care
resource representing a document's body	covid:0678ab3b16576deda330bf2472abda14e867eace#body_text
is schema:about of	named entity 'impact' named entity 'objectives' named entity 'Our' named entity 'severe' covid:arg/0678ab3b16576deda330bf2472abda14e867eace named entity 'ECMO' named entity 'optimal' named entity 'ECMO' named entity 'ECMO' named entity 'electrical impedance tomography' named entity 'acute respiratory distress syndrome' named entity 'EIT' named entity 'minute ventilation' named entity 'lungs' named entity 'first-line' named entity 'PEEP' named entity 'cannulation' named entity 'PEEP' named entity 'ventral' named entity 'ECMO' named entity 'hemodynamic' named entity 'post hoc test' named entity 'ventral' named entity 'PEEP' named entity 'ECMO' named entity 'ARDS' named entity 'body mass index' named entity 'PEEP' named entity '3, 4' named entity 'EIT' named entity 'minute ventilation' named entity 'ROIs' named entity 'PEEP' named entity 'San Diego' named entity 'lung volumes' named entity 'lung' named entity 'PEEP' named entity 'lung volumes' named entity 'ARDS' named entity 'lung' named entity 'decannulation' named entity 'lung' named entity 'PEEP' named entity 'EIT' named entity 'atelectasis' named entity 'viral pneumonia' named entity 'PEEP' named entity '4.2' named entity 'viral pneumonia' named entity 'PEEP' named entity 'ROIs' named entity 'PEEP' named entity 'PEEP' named entity 'lungs' named entity 'titrate' named entity 'bacterial pneumonia' named entity 'titration' named entity '5.4' named entity 'supine' named entity 'mmHg' named entity 'ECMO' named entity 'physiological effects' named entity 'EIT' named entity 'medical intensive care unit' named entity 'EIT' named entity 'PEEP' named entity 'lung' named entity 'PEEP' named entity 'lung' named entity 'ROIs' named entity 'Germany'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software