About: Activation and Role of NACHT, LRR, and PYD Domains-Containing Protein 3 Inflammasome in RNA Viral Infection

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About: Activation and Role of NACHT, LRR, and PYD Domains-Containing Protein 3 Inflammasome in RNA Viral Infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Activation and Role of NACHT, LRR, and PYD Domains-Containing Protein 3 Inflammasome in RNA Viral Infection
Creator	Wu, Yuzhang Wang, Jingxue Yu, Junyang Guo, Haitao Shen, Hao Com;, Wuyuzhang@yahoo Meunier, Etienne
Source	Medline; PMC
abstract	NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome activation and effects during ribonucleic acid (RNA) viral infection are the focus of a wide range of research currently. Both the pathogen-associated molecule pattern derived from virions and intracellular stress molecules involved in the process of viral infection lead to activation of the NLRP3 inflammasome, which in turn triggers inflammatory responses for antiviral defense and tissue healing. However, aberrant activation of the NLRP3 inflammasome can instead support viral pathogenesis and promote disease progression. Here, we summarize and expound upon the recent literature describing the molecular mechanisms underlying the activation and effects of the NLRP3 inflammasome in RNA viral infection to highlight how it provides protection against RNA viral infection.
has issue date	2017-10-31(xsd:dateTime)
bibo:doi	10.3389/fimmu.2017.01420
bibo:pmid	29163496
has license	cc-by
sha1sum (hex)	06485dd45c17460af629f7c74234bef914fbbabe
schema:url	https://doi.org/10.3389/fimmu.2017.01420
resource representing a document's title	Activation and Role of NACHT, LRR, and PYD Domains-Containing Protein 3 Inflammasome in RNA Viral Infection
has PubMed Central identifier	PMC5671583
has PubMed identifier	29163496
schema:publication	Front Immunol
resource representing a document's body	covid:06485dd45c17460af629f7c74234bef914fbbabe#body_text
is schema:about of	named entity 'effects' named entity 'lead' named entity 'activation' named entity 'inflammatory responses' named entity 'PROTEIN 3' named entity 'LRR' named entity 'FOCUS' named entity 'RNA' named entity 'INTRACELLULAR' named entity 'ROLE' named entity 'TURN' named entity 'VIRIONS' named entity 'LRR' named entity 'MOLECULAR' named entity 'INFLAMMASOME ACTIVATION' named entity 'INFLAMMATORY RESPONSES' named entity 'PROCESS' named entity 'HERE' named entity 'ABERRANT' named entity 'INFLAMMASOME' named entity 'CONTAINING' named entity 'HOW' named entity 'DISEASE PROGRESSION' named entity 'CONTAINING' named entity 'LEAD' named entity 'ANTIVIRAL' named entity 'MOLECULES' named entity 'RECENT' named entity 'PROTEIN 3' named entity 'MECHANISMS' named entity 'SUPPORT' named entity 'TISSUE HEALING' named entity 'VIRAL INFECTION' named entity 'THE NLRP3 INFLAMMASOME' named entity 'PROMOTE' named entity 'ASSOCIATED' named entity 'WIDE' named entity 'INVOLVED' named entity 'DESCRIBING' named entity 'DERIVED' named entity 'TRIGGERS' named entity 'PATTERN' named entity 'PATHOGEN' named entity 'ACTIVATION' named entity 'EFFECTS' named entity 'RANGE' named entity 'UNDERLYING' named entity 'STRESS' named entity 'VIRAL PATHOGENESIS' named entity 'CURRENTLY' named entity 'PROTECTION' named entity 'ACTIVATION' named entity 'VIRAL INFECTION' named entity 'MOLECULE' named entity 'DEFENSE' named entity 'RESEARCH' named entity 'LITERATURE' named entity 'RNA' named entity 'RIBONUCLEIC ACID' named entity 'PROVIDES' named entity 'aberrant' named entity 'derived' named entity 'inflammasome' named entity 'inflammasome' named entity 'tissue healing' named entity 'NLRP3' named entity 'protein' named entity 'inflammasome' named entity 'PYD' named entity 'molecular mechanisms' named entity 'RNA' named entity 'RNA' named entity 'LRR' named entity 'viral infection' named entity 'NLRP3'

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