About: A molecular survey for selected viral enteropathogens revealed a limited role of Canine circovirus in the development of canine acute gastroenteritis

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About: A molecular survey for selected viral enteropathogens revealed a limited role of Canine circovirus in the development of canine acute gastroenteritis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A molecular survey for selected viral enteropathogens revealed a limited role of Canine circovirus in the development of canine acute gastroenteritis
Creator	Buonavoglia, Canio Decaro, Nicola Desario, Costantina Elia, Gabriella Mari, Viviana Lorusso, Eleonora Lanave, Gianvito Dowgier, Giulia Lucente, Maria
Source	Elsevier; Medline; PMC
abstract	Canine circovirus (CanineCV) is a canine virus, whose pathogenetic role is still uncertain. Based on recent data suggesting its role as entheropathogen, a case-control study was conducted between 2013 and 2016 to investigate the association of CanineCV with gastroenteritis in dogs, alone or in combination with other viral pathogens, including canine parvovirus (CPV), canine coronavirus (CCoV) and canine distemper virus (CDV). A total of 219 dogs suffering from acute gastroenteritis disorders and 67 controls randomly recruited among healthy dogs or patients presenting without enteric signs were screened by a panel of real-time (RT-)PCR assays for CanineCV, CPV, CCoV and CDV. A high prevalence of viral infections was detected in dogs with gastroenteritis (77.16%), with CPV representing the most frequently detected enteropathogen, followed by CanineCV and CCoV. While CPV and CCoV infections displayed a strong association with occurrence of acute gastroenteritis (p < 0.00001), detection of CanineCV in control dogs (28.35%) occurred with prevalence comparable to that of clinical cases (32.42%), so that its correlation with gastrointestinal disease was not statistically supported (p = 0.530988). Different from the clinical cases, where co-infections were frequently observed, all positive samples from the control group contained single infections. Noteworthy, a significant association was calculated between co-infections with CanineCV and occurrence of acute gastroenteritis (p < 0.00001). This study supports the role of CanineCV as a co-pathogen in the development of gastrointestinal disease, mainly acting in synergism with other enteric viruses.
has issue date	2017-04-13(xsd:dateTime)
bibo:doi	10.1016/j.vetmic.2017.04.007
bibo:pmid	28532806
has license	no-cc
sha1sum (hex)	06214e7a233b353175d92e387934af3da7b5ce0d
schema:url	https://doi.org/10.1016/j.vetmic.2017.04.007
resource representing a document's title	A molecular survey for selected viral enteropathogens revealed a limited role of Canine circovirus in the development of canine acute gastroenteritis
has PubMed Central identifier	PMC7131434
has PubMed identifier	28532806
schema:publication	Vet Microbiol
resource representing a document's body	covid:06214e7a233b353175d92e387934af3da7b5ce0d#body_text
is schema:about of	named entity 'ROLE' named entity 'CANINE' named entity 'MOLECULAR' named entity 'ACUTE GASTROENTERITIS' named entity 'VIRAL' named entity 'SURVEY' named entity 'SELECTED' named entity 'LIMITED' named entity 'DEVELOPMENT' named entity 'REVEALED' named entity 'CANINE CIRCOVIRUS' named entity 'enteropathogens' named entity 'gastrointestinal disease' named entity 'canine' named entity 'Bexton' named entity 'canine distemper virus' named entity 'transport medium' named entity 'PCV-2' named entity 'acute gastroenteritis' named entity 'faeces' named entity 'Milan' named entity 'statistical analysis' named entity 'pathogen' named entity 'circoviruses' named entity 'viral pathogens' named entity 'statistical analysis' named entity 'gastroenteritis' named entity 'viral DNA' named entity '95% CI' named entity 'PCR' named entity 'porcine' named entity '2.45' named entity 'Japan' named entity 'statistical analysis' named entity 'RT-PCR' named entity 'minor groove binder' named entity 'viral RNA' named entity 'viral pathogens' named entity 'Takara Bio' named entity 'gastroenteritis' named entity 'gel electrophoresis' named entity 'viral replication' named entity 'pathogens' named entity 'nested PCR' named entity 'CDV' named entity '95% CI' named entity 'control group' named entity 'dependent variable' named entity 'clinical signs' named entity 'intestinal mucosa' named entity 'pathogenicity' named entity 'vaccination' named entity 'monomeric' named entity 'noroviruses' named entity '95% CI' named entity 'gastroenteritis' named entity 'infection' named entity 'immune response' named entity '95% CI' named entity 'Bio-Rad Laboratories' named entity 'Milan' named entity 'virus' named entity 'reoviruses' named entity '95% CI' named entity 'diarrhoea' named entity '95% CI' named entity 'Bio-Rad Laboratories' named entity 'enteric disease' named entity 'parasites' named entity 'enteric disease' named entity 'infection' named entity 'Italy' named entity '95% CI'

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