About: A baculovirus dual expression system-based vaccine confers complete protection against lethal challenge with H9N2 avian influenza virus in mice

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A baculovirus dual expression system-based vaccine confers complete protection against lethal challenge with H9N2 avian influenza virus in mice
Creator	Chen, Xiaowei Cheng, Xiaoliang Fan, Huiying Liao, Ming Lin, Wenyao Qi, Wenbao Ren, Tao Ye, Yu
Source	Medline; PMC
abstract	BACKGROUND: Avian influenza viruses of H9N2 subtype have become highly prevalent in avian species. Although these viruses generally cause only mild to moderate disease, they can infect a wide variety of species, including chickens, quail, turkeys, ducks, geese, pheasant, partridge, and pigeon, even transmitted to mammalian species, including humans, accelerating the efforts to devise protective strategies against them. RESULTS: The results showed that stronger immune responses were induced in a mouse model immunized with BV-Dual-HA than in those vaccinated with a DNA vaccine encoding the same antigen. Moreover, complete protection against lethal challenge with H9N2 virus was observed in mice. CONCLUSION: BV-Dual-HA could be utilized as a vaccine candidate against H9N2 virus infection.
has issue date	2011-06-04(xsd:dateTime)
bibo:doi	10.1186/1743-422x-8-273
bibo:pmid	21639929
has license	cc-by
sha1sum (hex)	052a16d442ede77ed4bdeaa05037270f251dedc4
schema:url	https://doi.org/10.1186/1743-422x-8-273
resource representing a document's title	A baculovirus dual expression system-based vaccine confers complete protection against lethal challenge with H9N2 avian influenza virus in mice
has PubMed Central identifier	PMC3120790
has PubMed identifier	21639929
schema:publication	Virol J
resource representing a document's body	covid:052a16d442ede77ed4bdeaa05037270f251dedc4#body_text
is schema:about of	named entity 'VACCINE' named entity 'turkeys' named entity 'AVIAN INFLUENZA VIRUS' named entity 'MAMMALIAN' named entity 'CAUSE' named entity 'COMPLETE' named entity 'ENCODING' named entity 'HIGHLY' named entity 'CONCLUSION' named entity 'DUAL' named entity 'PHEASANT' named entity 'VACCINATED' named entity 'TRANSMITTED' named entity 'VARIETY' named entity 'DUCKS' named entity 'BASED' named entity 'PROTECTION' named entity 'CHALLENGE' named entity 'DEVISE' named entity 'VIRUS INFECTION' named entity 'ANTIGEN' named entity 'COMPLETE' named entity 'LETHAL' named entity 'MICE' named entity 'DUAL' named entity 'H9N2 VIRUS' named entity 'OBSERVED' named entity 'AVIAN INFLUENZA' named entity 'VACCINE CANDIDATE' named entity 'GEESE' named entity 'VIRUSES' named entity 'THESE' named entity 'SUBTYPE' named entity 'TURKEYS' named entity 'INDUCED' named entity 'A DNA' named entity 'PROTECTION' named entity 'INFECT' named entity 'HUMANS' named entity 'IMMUNE RESPONSES' named entity 'GENERALLY' named entity 'MOUSE MODEL' named entity 'MILD TO MODERATE' named entity 'MODERATE DISEASE' named entity 'LETHAL' named entity 'BACKGROUND' named entity 'INCLUDING' named entity 'STRATEGIES' named entity 'PIGEON' named entity 'IMMUNIZED' named entity 'A MOUSE' named entity 'HAVE' named entity 'PARTRIDGE' named entity 'WIDE' named entity 'DNA VACCINE' named entity 'CHICKENS' named entity 'PREVALENT' named entity 'MICE' named entity 'SPECIES' named entity 'RESULTS' named entity 'INFLUENZA VIRUSES' named entity 'QUAIL' named entity 'CHALLENGE' named entity 'EXPRESSION SYSTEM' named entity 'BACULOVIRUS' named entity 'COULD BE' named entity 'AVIAN' covid:arg/052a16d442ede77ed4bdeaa05037270f251dedc4 named entity 'Although' named entity 'immunized' named entity 'virus' named entity 'DNA vaccine' named entity 'Avian influenza' named entity 'avian influenza'

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