About: A novel full-length isoform of murine pregnancy-specific glycoprotein 16 (psg16) is expressed in the brain but does not mediate murine coronavirus (MHV) entry

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About: A novel full-length isoform of murine pregnancy-specific glycoprotein 16 (psg16) is expressed in the brain but does not mediate murine coronavirus (MHV) entry Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A novel full-length isoform of murine pregnancy-specific glycoprotein 16 (psg16) is expressed in the brain but does not mediate murine coronavirus (MHV) entry
Creator	Weiss, Susan Richardson, Chelsea Phillips, Judith Kuo, & I-Ting
Source	Medline; PMC
abstract	The mouse pregnancy-specific glycoprotein 16 (PSG16) has been reported to be an alternative receptor for mouse hepatitis virus (MHV), some strains of which cause encephalitis in mice lacking the canonical receptor CEACAM1a. The known isoforms of PSG16 are N-terminally truncated relative to other PSG family proteins and are expressed in neurons as well as in the placenta. We have cloned a novel full-length isoform of psg16 that is also expressed in the brain, placenta, and retina but, like the truncated form, lacks MHV receptor activity when expressed on 293T cells, suggesting that PSG16 does not mediate CEACAM1a-independent spread of MHV.
has issue date	2012-02-03(xsd:dateTime)
bibo:doi	10.1007/s13365-012-0081-6
bibo:pmid	22302612
has license	bronze-oa
sha1sum (hex)	048e7e6bb5b0484b0b5dfb154c2538495dd58e11
schema:url	https://doi.org/10.1007/s13365-012-0081-6
resource representing a document's title	A novel full-length isoform of murine pregnancy-specific glycoprotein 16 (psg16) is expressed in the brain but does not mediate murine coronavirus (MHV) entry
has PubMed Central identifier	PMC3368079
has PubMed identifier	22302612
schema:publication	Journal of NeuroVirology
resource representing a document's body	covid:048e7e6bb5b0484b0b5dfb154c2538495dd58e11#body_text
is schema:about of	named entity 'canonical' named entity 'mediate' named entity 'MHV' named entity 'mouse' named entity 'glycoprotein' named entity 'MHV' named entity 'DOES NOT' named entity 'SPREAD' named entity 'BUT' named entity 'MOUSE' named entity 'KNOWN' named entity 'ENCEPHALITIS' named entity 'CLONED' named entity 'EXPRESSED' named entity 'ALTERNATIVE' named entity 'FAMILY' named entity 'MOUSE HEPATITIS VIRUS' named entity 'STRAINS' named entity 'ISOFORM' named entity 'THE BRAIN' named entity 'LACKING' named entity 'PSG' named entity 'RETINA' named entity 'INDEPENDENT' named entity 'PLACENTA' named entity 'THE BRAIN' named entity 'LENGTH' named entity 'NOVEL' named entity '293T CELLS' named entity 'PREGNANCY-SPECIFIC GLYCOPROTEIN' named entity 'PROTEINS' named entity 'MEDIATE' named entity 'ENTRY' named entity 'EXPRESSED' named entity 'MURINE CORONAVIRUS' named entity 'ISOFORM' named entity 'LENGTH' named entity 'NOVEL' named entity 'DOES NOT' named entity 'MICE' named entity 'REPORTED' named entity 'NEURONS' named entity 'TRUNCATED' named entity 'LIKE' named entity 'RECEPTOR' named entity 'ISOFORMS' named entity 'RELATIVE TO' named entity 'HAVE' named entity 'CAUSE' named entity 'RECEPTOR ACTIVITY' named entity 'PSG16' named entity 'FORM' named entity 'PREGNANCY-SPECIFIC GLYCOPROTEIN' named entity 'BUT' named entity 'MURINE' named entity 'MEDIATE' named entity 'expressed' named entity 'isoform' named entity 'neurons' named entity 'strains' named entity 'truncated' named entity 'virus' named entity 'receptor' named entity 'receptor' named entity 'MHV' named entity 'pregnancy' named entity 'glycoprotein' named entity 'mice' named entity 'MHV' named entity 'retina' named entity 'cloned' named entity 'murine coronavirus' named entity 'exon' named entity 'fetus' named entity 'DTT' named entity 'placental' named entity 'isoforms' named entity 'African green monkey'

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