About: Could preventive intranasal interferon lower the morbidity in children prone to respiratory illness?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Could preventive intranasal interferon lower the morbidity in children prone to respiratory illness?
Creator	Ma, Douglas, Robert Miles, Helen Moore, Brian Pinnock, Carole
source	PMC
abstract	Recent studies have demonstrated that rhinovirus infections can be prevented in the family setting through use of intranasal interferon sprays which are commenced when another family member develops a cold. One hundred and twenty‐seven children aged 4–9 years who had been hospitalized during their first year of life for severe infections caused by respiratory syncytial virus were studied virologically and epidemiologically during a seven‐month period which included the winter months. The hypothesis was that a significant part of their respiratory morbidity would be preventable by a contact prophylaxis approach using intranasal interferon. However, the findings suggest that a preventive approach of this kind would not substantially reduce the burden of respiratory illness in these children because: the target children themselves more often introduced illness into the family than did other household members; rhinovirus infections preventable by interferon were associated with little lower respiratory morbidity; and rhinoviruses were minor contributors to the total respiratory illness burden in these respiratory illness‐prone children.
has issue date	1990-05-01(xsd:dateTime)
bibo:doi	10.5694/j.1326-5377.1990.tb125353.x
bibo:pmid	1692602
has license	no-cc
sha1sum (hex)	0314c2add7cb7f3ced0d2968846d02df05741e15
schema:url	https://doi.org/10.5694/j.1326-5377.1990.tb125353.x
resource representing a document's title	Could preventive intranasal interferon lower the morbidity in children prone to respiratory illness?
has PubMed Central identifier	PMC7168430
has PubMed identifier	1692602
schema:publication	Med J Aust
resource representing a document's body	covid:0314c2add7cb7f3ced0d2968846d02df05741e15#body_text
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