About: Rapid review protocol: zinc for the prevention or treatment of COVID-19 and other coronavirus-related respiratory tract infections

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About: Rapid review protocol: zinc for the prevention or treatment of COVID-19 and other coronavirus-related respiratory tract infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Rapid review protocol: zinc for the prevention or treatment of COVID-19 and other coronavirus-related respiratory tract infections
Creator	Hunter, Jennifer Mertz, Dominik Prof, A Arentz, Susan Beardsley, Jennifer Goldenberg, Joshua Yang, Guoyan Ba, Jennifer Ba, Guoyan Bsc, Stephen Professor, Emeritus
Source	Elsevier; Medline; PMC
abstract	Abstract Background . The global COVID-19 pandemic has prompted an urgent search for effective interventions. SARS-CoV-2 mortality/morbidity risk increases with age and for those chronic disease co-morbidities, both of which are associated with lower zinc status, as is the risk of infection. Methods Rapid review methods will be applied to a systematic review of zinc for the prevention or treatment of SARS-CoV-2 and viral respiratory tract infections in humans. Included are published studies reporting randomised and quasi-randomised controlled trials that compare zinc intervention to placebo and/or other comparator interventions. English and Chinese language databases will be searched for primary studies of viral respiratory tract infections and clinical trial registries for SARS-CoV-2 infections. Due to concerns about indirectness, studies evaluating non-SARS-CoV-2 coronavirus infections will be rated down by one level, and non-specific or confirmed non-coronavirus viral infections will be rated down by two levels. Review constraints include 1) using Google translate when screening articles published in languages other than English or Chinese and limited translation 2) following calibration, only one reviewer will screen articles, extract data, appraise quality and conduct the analysis, 3) prioritising data extraction and meta-analyses of SARS-CoV-2 studies and critical outcomes of other viral infections, followed by high risk groups and 4) reporting important preliminary findings prior to peer review if necessary. Discussion . The application of these rapid review methods and broadening the inclusion criteria to include other coronavirus-related viral respiratory tract infections aims to enable a timely evidence appraisal of priority research questions and dissemination of results.
has issue date	2020-06-23(xsd:dateTime)
bibo:doi	10.1016/j.imr.2020.100457
bibo:pmid	32690999
has license	els-covid
sha1sum (hex)	0122e410d1539f404a19761b90e37387be0a9617
schema:url	https://doi.org/10.1016/j.imr.2020.100457
resource representing a document's title	Rapid review protocol: zinc for the prevention or treatment of COVID-19 and other coronavirus-related respiratory tract infections
has PubMed Central identifier	PMC7308745
has PubMed identifier	32690999
schema:publication	Integr Med Res
resource representing a document's body	covid:0122e410d1539f404a19761b90e37387be0a9617#body_text
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