About: perturb function

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An Entity of Type : owl:Class, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Class
label	perturb function
subClassOf	function
described by	proxy:entity/http/purl.obolibrary.org/obo/obi.owl
term editor	Melanie Courtot Bill Bug Daniel Schober Frank Gibson
definition	A perturb function is a function that disrupts the normal function of a system induced through either internal or external means. External means of perturbation include: (1) displacement fields in the physical sense - e.g., temperature change, osmotic shock, pressure change; (2) application of small molecules such as drugs or toxins to perturb the function of specific pathways or application of surfactants to perturb the normal function of plasma membrane. Internal means of perturbation include: (1) manipulation of gene function via gene knockout or transcript knockdown via RNAi; (2) directed genetic mutation leading to minimal aa alterations that interfere with peptide function.
definition source	wikipedia-en:Perturbation_biology(en)
editor preferred term	perturb function
has curation status	ready for release
is someValuesFrom of	nodeID://b665186372 nodeID://b665199395 nodeID://b665199422 nodeID://b665199430 nodeID://b665199437 nodeID://b665210669 nodeID://b665223692 nodeID://b665223719 nodeID://b665223727 nodeID://b665223734 nodeID://b665809191 nodeID://b665822214 nodeID://b665822241 nodeID://b665822249 nodeID://b665822256 nodeID://b665833488 nodeID://b665846511 nodeID://b665846538 nodeID://b665846546 nodeID://b665846553 nodeID://b665865703 nodeID://b665878726 nodeID://b665878753 nodeID://b665878761 nodeID://b665878768 nodeID://b665890000 nodeID://b665903023 nodeID://b665903050 nodeID://b665903058 nodeID://b665903065 nodeID://b665914297 nodeID://b665927320 nodeID://b665927347 nodeID://b665927355 nodeID://b665927362 nodeID://b665938594 nodeID://b665951617 nodeID://b665951644 nodeID://b665951652 nodeID://b665951659 nodeID://b669074357 nodeID://b669087250 nodeID://b669087277 nodeID://b669087285 nodeID://b669087292 nodeID://b669098542 nodeID://b669111435 nodeID://b669111462 nodeID://b669111470 nodeID://b669111477
is topic of	Ontology for Biomedical Investigations

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