About: Quantitative Links Between Arsenic Exposure and Influenza A (H1N1) Infection‐Associated Lung Function Exacerbations Risk

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Quantitative Links Between Arsenic Exposure and Influenza A (H1N1) Infection‐Associated Lung Function Exacerbations Risk
Creator	Chen, Szu-Chieh Chen, Wei-Yu Cheng, Yi-Hsien Hsieh, Nan-Hung Liao, Chung-Min Chio, Chia-Pin
Source	Medline; PMC
abstract	The objective of this study was to link arsenic exposure and influenza A (H1N1) infection‐induced respiratory effects to assess the impact of arsenic‐contaminated drinking water on exacerbation risk of A (H1N1)‐associated lung function. The homogeneous Poisson process was used to approximate the related processes between arsenic exposure and influenza‐associated lung function exacerbation risk. We found that (i) estimated arsenic‐induced forced expiratory volume in 1 second (FEV(1)) reducing rates ranged from 0.116 to 0.179 mL/μg for age 15–85 years, (ii) estimated arsenic‐induced A (H1N1) viral load increasing rate was 0.5 mL/μg, (iii) estimated A (H1N1) virus‐induced FEV(1) reducing rate was 0.10 mL/logTCID50, and (iv) the relationship between arsenic exposure and A (H1N1)‐associated respiratory symptoms scores (RSS) can be described by a Hill model. Here we showed that maximum RSS at day 2 postinfection for Taiwan, West Bengal (India), and the United States were estimated to be in the severe range of 0.83, 0.89, and 0.81, respectively, indicating that chronic arsenic exposure and A (H1N1) infection together are most likely to pose potential exacerbations risk of lung function, although a 50% probability of lung function exacerbations risk induced by arsenic and influenza infection was within the mild and moderate ranges of RSS at day 1 and 2 postinfection. We concluded that avoidance of drinking arsenic‐containing water could significantly reduce influenza respiratory illness and that need will become increasingly urgent as the novel H1N1 pandemic influenza virus infects people worldwide.
has issue date	2011-02-01(xsd:dateTime)
bibo:doi	10.1111/j.1539-6924.2010.01575.x
bibo:pmid	21284682
has license	no-cc
sha1sum (hex)	fdb94e59b4aeee3c39ea906dfef8a165df22aa8c
schema:url	https://doi.org/10.1111/j.1539-6924.2010.01575.x
resource representing a document's title	Quantitative Links Between Arsenic Exposure and Influenza A (H1N1) Infection‐Associated Lung Function Exacerbations Risk
has PubMed Central identifier	PMC7169133
has PubMed identifier	21284682
schema:publication	Risk Anal
resource representing a document's body	covid:fdb94e59b4aeee3c39ea906dfef8a165df22aa8c#body_text
is schema:about of	named entity 'reducing' named entity 'risk' named entity 'lung function' named entity 'risk' named entity 'Links' named entity 'RATES' named entity 'HILL' named entity 'VIRAL LOAD' named entity '116' named entity 'REDUCING' named entity 'POTENTIAL' named entity 'IMPACT' named entity 'day' named entity 'respiratory illness' named entity 'homogeneous' named entity 'arsenic' named entity 'risk' named entity 'Here' named entity 'H1N1' named entity 'pulmonary diseases' named entity 'arsenic' named entity 'arsenic' named entity 'arsenic exposure' named entity 'arsenic exposure' named entity 'H1N1' named entity 'drinking water supplies' named entity 'arsenic' named entity 'Quantitative' named entity 'United States' named entity 'influenza' named entity 'RSS' named entity 'lung function' named entity 'forced expiratory volume' named entity 'influenza infection' named entity 'Taiwan' named entity 'India' named entity 'FEV' named entity 'lung function' named entity 'H1N1' named entity 'arsenic' named entity 'Exacerbations' named entity 'Arsenic Exposure' named entity 'drinking water' named entity 'lung function' named entity 'influenza' named entity 'arsenic' named entity 'arsenic' named entity 'probability density function' named entity '2.45' named entity 'lung function' named entity 'virus infections' named entity 'symptom' named entity 'risk management' named entity 'respiratory symptoms' named entity 'RSS' named entity 'FVC' named entity 'arsenic' named entity 'lognormal distribution' named entity 'dose-response model' named entity 'arsenic' named entity 'tobacco smoking' named entity 'respiratory symptoms' named entity 'lung function' named entity 'Kozul' named entity 'arsenic' named entity 'nasal stuffiness' named entity 'Epidemiological data' named entity 'lung function' named entity 'dose-response' named entity 'Poisson processes' named entity 'arsenic' named entity 'H1N1' named entity 'RSS' named entity 'drinking water' named entity 'influenza' named entity 'Hill coefficient'

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