About: Advancement and applications of peptide phage display technology in biomedical science

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Advancement and applications of peptide phage display technology in biomedical science
Creator	Liu, I-Ju Wu, Han-Chung Lu, Ruei-Min Wu, Chien-Hsun
Source	Medline; PMC
abstract	Combinatorial phage library is a powerful research tool for high-throughput screening of protein interactions. Of all available molecular display techniques, phage display has proven to be the most popular approach. Screening phage-displayed random peptide libraries is an effective means of identifying peptides that can bind target molecules and regulate their function. Phage-displayed peptide libraries can be used for (i) B-cell and T-cell epitope mapping, (ii) selection of bioactive peptides bound to receptors or proteins, disease-specific antigen mimics, peptides bound to non-protein targets, cell-specific peptides, or organ-specific peptides, and (iii) development of peptide-mediated drug delivery systems and other applications. Targeting peptides identified using phage display technology may be useful for basic research and translational medicine. In this review article, we summarize the latest technological advancements in the application of phage-displayed peptide libraries to applied biomedical sciences.
has issue date	2016-01-19(xsd:dateTime)
bibo:doi	10.1186/s12929-016-0223-x
bibo:pmid	26786672
has license	cc-by
sha1sum (hex)	faa8c6b399eff710bae62ce297e56c19fe212e74
schema:url	https://doi.org/10.1186/s12929-016-0223-x
resource representing a document's title	Advancement and applications of peptide phage display technology in biomedical science
has PubMed Central identifier	PMC4717660
has PubMed identifier	26786672
schema:publication	J Biomed Sci
resource representing a document's body	covid:faa8c6b399eff710bae62ce297e56c19fe212e74#body_text
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