About: SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study
Creator	Smith, Stephanie Kelly, Matthew Woods, Christopher Affiliations, Gurley, Thaddeus Permar, Sallie Steinbach, William Turner, Nicholas Denny, Thomas Moody, M Walter, Emmanuel Cunningham, Coleen Rotta, Alexandre Aquino, Jhoanna Bose, Shree Carr, Stuart Chambers, Hailey Crew, Carter Cunningham, Hannah De Naeyer, Nicole Demarco, C Griffin, S Heston, Sarah Hurst, Jillian Jenkins, Kirsten Louzao, Raul Lugo, Debra Pfeiffer, Trevor Price, Meghan Rodriguez, Javier Suarez, Liliana
Source	MedRxiv
abstract	BACKGROUND: Children with SARS-CoV-2 infection typically have mild symptoms that do not require medical attention, leaving a gap in our understanding of the spectrum of illnesses that the virus causes in children. METHODS: We conducted a prospective cohort study of children and adolescents (<21 years of age) with a SARS-CoV-2-infected close contact. We collected nasopharyngeal or nasal swabs at enrollment and tested for SARS-CoV-2 using a real-time PCR assay. RESULTS: Of 382 children, 293 (77%) were SARS-CoV-2-infected. SARS-CoV-2-infected children were more likely to be Hispanic (p<0.0001), less likely to have asthma (p=0.005), and more likely to have an infected sibling contact (p=0.001) than uninfected children. Children ages 6-13 years were frequently asymptomatic (39%) and had respiratory symptoms less often than younger children (29% vs. 48%; p=0.01) or adolescents (29% vs. 60%; p<0.0001). Compared to children ages 6-13 years, adolescents more frequently reported influenza-like (61% vs. 39%; p<0.0001), gastrointestinal (27% vs. 9%; p=0.002), and sensory symptoms (42% vs. 9%; p<0.0001), and had more prolonged illnesses [median (IQR) duration: 7 (4, 12) vs. 4 (3, 8) days; p=0.01]. Despite the age-related variability in symptoms, we found no differences in nasopharyngeal viral load by age or between symptomatic and asymptomatic children. CONCLUSIONS: Hispanic ethnicity and an infected sibling close contact are associated with increased SARS-CoV-2 infection risk among children, while asthma is associated with decreased risk. Age-related differences in the clinical manifestations of SARS-CoV-2 infection must be considered when evaluating children for COVID-19 and in developing screening strategies for schools and childcare settings.
has issue date	2020-08-21(xsd:dateTime)
bibo:doi	10.1101/2020.08.18.20166835
has license	medrxiv
sha1sum (hex)	f6e88a1f8a24cb2020e5f9175b82eaf075720e34
schema:url	https://doi.org/10.1101/2020.08.18.20166835
resource representing a document's title	SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study
resource representing a document's body	covid:f6e88a1f8a24cb2020e5f9175b82eaf075720e34#body_text
is schema:about of	named entity 'leaving' named entity 'SARS-COV-2 INFECTION' named entity 'ILLNESSES' named entity 'medical attention' named entity 'SARS-CoV-2' named entity 'infection' named entity 'correlation' named entity 'symptom' named entity 'SARS-CoV-2' named entity 'nasopharyngeal' named entity '3.8' named entity 'respiratory symptoms' named entity 'medRxiv' named entity 'gastrointestinal' named entity 'analysis of data' named entity 'symptom' named entity 'electronic medical records' named entity 'infection' named entity 'virus' named entity 'follow-up' named entity 'SARS-CoV-2' named entity 'CC-BY-NC-ND 4.0' named entity 'medRxiv' named entity 'Gene Expression' named entity 'nasopharyngeal' named entity 'SARS-CoV-2' named entity 'medRxiv' named entity 'SARS-CoV-2' named entity 'attack rate' named entity 'viral load' named entity 'Nasopharynx' named entity 'viral load' named entity 'respiratory symptoms' named entity 'SARS-CoV-2' named entity 'clinical care' named entity 'infection' named entity 'Hispanic' named entity 'Real-Time PCR' named entity 'epidemiological' named entity 'quantile-quantile plot' named entity 'efficient transmission' named entity 'asthma' named entity 'virus' named entity 'p=0.01' named entity 'COVID' named entity 'COVID' named entity 'infection' named entity 'SARS-CoV-2' named entity 'nucleic acid' named entity 'risk factor' named entity 'CDC' named entity 'PCR' named entity 'CC-BY-NC-ND 4.0' named entity 'peer review' named entity 'cDNA'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software