About: Current management and outcome of tracheobronchial malacia and stenosis presenting to the paediatric intensive care unit

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About: Current management and outcome of tracheobronchial malacia and stenosis presenting to the paediatric intensive care unit Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Current management and outcome of tracheobronchial malacia and stenosis presenting to the paediatric intensive care unit
Creator	Elliott, Martin Inwald, David Mok, Quen Roebuck, Derek
Source	PMC
abstract	Objective: To identify factors associated with mortality and prolonged ventilatory requirements in patients admitted to our paediatric intensive care unit (PICU) with tracheobronchial malacia and stenosis diagnosed by dynamic contrast bronchograms. Design: Retrospective review. Setting: Tertiary paediatric intensive care unit. Patients: Forty-eight cases admitted to our PICU over a 5-year period in whom a diagnosis of tracheobronchial malacia or stenosis was made by dynamic contrast bronchography (1994–1999). Interventions: Conservative management, tracheostomy and long-term ventilation, surgical correction, internal or external airway stenting. Measurements and results: Recording of clinical details, length of invasive ventilation and appearance at contrast bronchography. Five groups of patients were defined: isolated primary airway pathology (n=7), ex-premature infants (n=11), vascular rings (n=9), complex cardiac and/or syndromic pathology (n=17) and tracheo-oesophageal fistulae (n=4). The overall mortality was 29%. Median length of invasive ventilation in survivors was 38 days and in patients who died 45. Mortality was highest in the patients with complex cardiac and/or syndromic pathology (p=0.039 Cox regression analysis) but was not related to any other factor. Patients with stenosis required a significantly longer period of ventilatory support (median length of ventilation 59 days) than patients with malacia (39 days). Conclusions: Length of ventilation and bronchographic diagnosis did not predict survival. The only factor found to contribute significantly to mortality was the presence of complex cardiac and/or syndromic pathology. However, patients with stenosis required longer ventilatory support than patients with malacia.
has issue date	2001-02-16(xsd:dateTime)
bibo:doi	10.1007/s001340000822
bibo:pmid	11398700
has license	no-cc
sha1sum (hex)	f620ee1003c6abad7b4f619ba5972bd3eab7269b
schema:url	https://doi.org/10.1007/s001340000822
resource representing a document's title	Current management and outcome of tracheobronchial malacia and stenosis presenting to the paediatric intensive care unit
has PubMed Central identifier	PMC7094939
has PubMed identifier	11398700
schema:publication	Intensive Care Med
resource representing a document's body	covid:f620ee1003c6abad7b4f619ba5972bd3eab7269b#body_text
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