About: Control of cryptosporidiosis in neonatal calves: Use of halofuginone lactate in two different calf rearing systems

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About: Control of cryptosporidiosis in neonatal calves: Use of halofuginone lactate in two different calf rearing systems Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Control of cryptosporidiosis in neonatal calves: Use of halofuginone lactate in two different calf rearing systems
Creator	Berkvens, D De Waele, V Mulcahy, G Murphy, T Speybroeck, N
topic	covid:f592a8a27662ba15bf4af4b3bdb0e71c3dc0e88e#this
Source	Elsevier; Medline; PMC
abstract	Abstract To date there is no effective treatment for bovine cryptosporidiosis. This study describes the use of halofuginone lactate in preventing cryptosporidiosis in naturally infected neonatal calves on a dairy farm with a high prevalence of infection. The animals were kept in two different calf rearing systems. A randomized double-blind trial was carried out with 32 naturally infected calves, divided into four groups. The two prophylactic halofuginone lactate treated groups were kept in either individual or group pens. Similarly, the animals receiving the placebo were housed in either individual pens or together in a large pen. A total of ten faecal samples were collected periodically during the 28 days study from each calf and tested for the presence of Cryptosporidium spp. using microscopic and molecular methods. Generalized estimating equations models were used to determine if the effects of the various treatments and/or rearing systems on the presence of diarrhoea and infection were statistically significant. Further analysis (classification trees models) was carried out to explore possible risk factors for cryptosporidiosis and interactions between treatments and rearing systems. Halofuginone lactate was shown to be effective in reducing clinical signs of cryptosporidiosis and environmental contamination. However, the treatment did not delay the onset of diarrhoea and did not reduce the risk of infection amongst calves reared together in a highly contaminated environment. The use of halofuginone lactate in combination with good hygienic measures, such as rearing animals in clean individual pens, was the most effective method to reduce the risk of cryptosporidiosis amongst 7–13 days old calves. It was concluded that the control of the parasite could be achieved by the combination of using effective preventive drugs, such as halofuginone lactate and good animal husbandry procedures.
has issue date	2010-09-01(xsd:dateTime)
bibo:doi	10.1016/j.prevetmed.2010.06.017
bibo:pmid	20692058
has license	els-covid
sha1sum (hex)	f592a8a27662ba15bf4af4b3bdb0e71c3dc0e88e
schema:url	https://doi.org/10.1016/j.prevetmed.2010.06.017
resource representing a document's title	Control of cryptosporidiosis in neonatal calves: Use of halofuginone lactate in two different calf rearing systems
has PubMed Central identifier	PMC7114106
has PubMed identifier	20692058
schema:publication	Preventive Veterinary Medicine
resource representing a document's body	covid:f592a8a27662ba15bf4af4b3bdb0e71c3dc0e88e#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/f592a8a27662ba15bf4af4b3bdb0e71c3dc0e88e
is schema:about of	named entity 'HALOFUGINONE LACTATE' named entity 'environmental contamination' named entity 'pen.' named entity 'statistically' named entity 'measures' named entity 'preventing' named entity 'prophylactic' named entity 'divided' named entity 'lactate' named entity 'contaminated' named entity 'calves' named entity 'SYSTEMS' named entity 'CALVES' named entity 'OLD' named entity 'GROUP' named entity 'DIVIDED' named entity 'ENVIRONMENTAL CONTAMINATION' named entity 'DIFFERENT' named entity 'SPP' named entity 'CALF' named entity 'STUDY' named entity 'RISK OF INFECTION' named entity 'PENS' named entity 'TESTED FOR' named entity 'SAMPLES' named entity 'USED' named entity 'LARGE' named entity 'PREVENTING' named entity 'GENERALIZED' named entity 'EFFECTIVE' named entity 'EITHER' named entity 'EFFECTS' named entity 'MICROSCOPIC' named entity 'COMBINATION' named entity 'ANIMAL HUSBANDRY' named entity 'USE OF' named entity 'RISK OF' named entity 'HOUSED' named entity 'PERIODICALLY' named entity 'PROPHYLACTIC' named entity 'PROCEDURES' named entity 'DIFFERENT' named entity 'CRYPTOSPORIDIOSIS' named entity 'PRESENCE OF' named entity 'CONTROL' named entity 'REDUCING' named entity 'CARRIED' named entity 'PARASITE' named entity 'METHOD' named entity 'DETERMINE' named entity 'INTERACTIONS' named entity 'MEASURES' named entity 'DAYS' named entity 'STATISTICALLY SIGNIFICANT' named entity 'RECEIVING' named entity 'FAECAL' named entity 'ANIMALS' named entity 'DATE' named entity 'DELAY' named entity 'METHODS' named entity 'VARIOUS' named entity 'TREATMENT' named entity 'TREES' named entity 'NEONATAL' named entity 'INDIVIDUAL' named entity 'PLACEBO' named entity 'ONSET OF' named entity 'POSSIBLE' named entity 'CALVES' named entity 'ENVIRONMENT' named entity 'TREATMENTS' named entity 'PEN.' named entity 'HIGHLY' named entity 'CRYPTOSPORIDIUM' named entity 'HALOFUGINONE LACTATE'

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