About: Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility

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About: Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020
Creator	Duchin, Jeffrey Kay, Meagan Page, C Russell, Denny Stone, Nimalie Bardossy, Ana Jernigan, John Clark, Thomas Carlson, Christina Jacobs, Jesica Brostrom-Smith, Claire Clark, Shauna Hiatt, Brian Honein, Margaret Lewis, James Oakley, Lisa Reddy, Sujan Arons, Melissa Bell, Jeneita Chisty, Zeshan Gant, Jessica Harney, Josh Hatfield, Kelly James, Allison Kimball, Anne Libby, ; Mmed, Spicer, Kevin Tanwar, Sukarma Taylor, Joanne Mclaughlin, Heather Methner, ;
source	Medline; PMC
abstract	Older adults are susceptible to severe coronavirus disease 2019 (COVID-19) outcomes as a consequence of their age and, in some cases, underlying health conditions (1). A COVID-19 outbreak in a long-term care skilled nursing facility (SNF) in King County, Washington that was first identified on February 28, 2020, highlighted the potential for rapid spread among residents of these types of facilities (2). On March 1, a health care provider at a second long-term care skilled nursing facility (facility A) in King County, Washington, had a positive test result for SARS-CoV-2, the novel coronavirus that causes COVID-19, after working while symptomatic on February 26 and 28. By March 6, seven residents of this second facility were symptomatic and had positive test results for SARS-CoV-2. On March 13, CDC performed symptom assessments and SARS-CoV-2 testing for 76 (93%) of the 82 facility A residents to evaluate the utility of symptom screening for identification of COVID-19 in SNF residents. Residents were categorized as asymptomatic or symptomatic at the time of testing, based on the absence or presence of fever, cough, shortness of breath, or other symptoms on the day of testing or during the preceding 14 days. Among 23 (30%) residents with positive test results, 10 (43%) had symptoms on the date of testing, and 13 (57%) were asymptomatic. Seven days after testing, 10 of these 13 previously asymptomatic residents had developed symptoms and were recategorized as presymptomatic at the time of testing. The reverse transcription-polymerase chain reaction (RT-PCR) testing cycle threshold (Ct) values indicated large quantities of viral RNA in asymptomatic, presymptomatic, and symptomatic residents, suggesting the potential for transmission regardless of symptoms. Symptom-based screening in SNFs could fail to identify approximately half of residents with COVID-19. Long-term care facilities should take proactive steps to prevent introduction of SARS-CoV-2 (3). Once a confirmed case is identified in an SNF, all residents should be placed on isolation precautions if possible (3), with considerations for extended use or reuse of personal protective equipment (PPE) as needed (4).
has issue date	2020-04-03(xsd:dateTime)
bibo:doi	10.15585/mmwr.mm6913e1
bibo:pmid	32240128
has license	cc-by
sha1sum (hex)	f122876a8ca4f4ee0b3b77965859502dbf79e938
schema:url	https://doi.org/10.15585/mmwr.mm6913e1
resource representing a document's title	Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020
has PubMed Central identifier	PMC7119514
has PubMed identifier	32240128
schema:publication	MMWR Morb Mortal Wkly Rep
resource representing a document's body	covid:f122876a8ca4f4ee0b3b77965859502dbf79e938#body_text
is schema:about of	named entity 'Morbidity' named entity 'March' named entity 'Asymptomatic' named entity 'Mortality' named entity 'March 2020' named entity 'SARS-CoV-2' named entity 'neurologic conditions' named entity 'Symptom' named entity 'diarrhea' named entity 'dizziness' named entity 'symptom' named entity 'Demographic characteristics' named entity 'SARS-CoV-2' named entity 'viral RNA' named entity 'Public Health' named entity 'positive test' named entity 'infection prevention and control' named entity 'nausea' named entity 'cough' named entity 'index case' named entity 'symptom' named entity 'PPE' named entity 'signs and symptoms' named entity 'COVID' named entity 'SNF' named entity 'COVID' named entity 'nucleocapsid protein' named entity 'SARS-CoV-2' named entity 'independent living' named entity 'personal protective equipment (PPE' named entity 'dizziness' named entity 'March 1' named entity 'PPE' named entity 'King County' named entity 'King County, Washington' named entity 'cohorting' named entity 'nausea' named entity 'cough' named entity 'long-term care' named entity 'long-term care facilities' named entity 'myalgia' named entity 'transmission-based precautions' named entity 'SARS-CoV-2' named entity 'asymptomatic' named entity 'infection' named entity 'public health' named entity 'SNF' named entity 'cohorting' named entity 'COVID' named entity 'N95'

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