About: Viral Findings in Children under the Age of Two Years with Expiratory Difficulties

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral Findings in Children under the Age of Two Years with Expiratory Difficulties
Creator	Halonen, P Halonen, M Kleemola, M Kleemola, P Korppi, Abstract Korppi, M Launiala, K Launiala, M
Source	PMC
abstract	ABSTRACT. Viral findings were prospectively studied in lower respiratory tract infections in small children with and without expiratory difficulties. On first admission, a viral aetiology was found in 71 of 127 children (56%). On re‐admission, a viral etiology was found in only two of 31 cases (6%). Respiratory syncytial viruses (RSV) were responsible for 71% of the cases with viral diagnoses. A recently‐developed method for the direct detection of viral antigens in nasopharyngeal specimens by radio‐immunoassay was more sensitive than complement fixation serology, especially in patients aged less than six months. Viral diagnosis was reached using this new method alone in 43% of infections caused by RSV and in 27% of infections caused by other viruses. In children under six months, RSV were found in 89% by direct antigen detection and in 22% by serology. We suggest that direct antigen detection should be used as the primary virological method in small children with lower respiratory tract infections. The aetiological agents were the same in cases with and without expiratory difficulties, RSV being found in about 40% of children in both instances. It is concluded that host factors are critical to the development of expiratory difficulties.
has issue date	2008-01-21(xsd:dateTime)
bibo:doi	10.1111/j.1651-2227.1986.tb10230.x
has license	no-cc
sha1sum (hex)	edc3f166dce9f249f51efde16e1d996e2696245f
schema:url	https://doi.org/10.1111/j.1651-2227.1986.tb10230.x
resource representing a document's title	Viral Findings in Children under the Age of Two Years with Expiratory Difficulties
has PubMed Central identifier	PMC7188333
schema:publication	Acta Paediatr
resource representing a document's body	covid:edc3f166dce9f249f51efde16e1d996e2696245f#body_text
is schema:about of	named entity 'respiratory tract infections' named entity 'Respiratory' named entity 'CHILDREN' named entity 'VIRAL' named entity 'syncytial' named entity 'viruses' named entity 'aetiology' named entity '1986' named entity 'prospectively' named entity 'Viral' named entity 'herpes simplex virus' named entity 'serology' named entity 'pneumonia' named entity 'RSV' named entity 'clinical signs' named entity 'serology' named entity 'viruses' named entity 'influenza virus' named entity 'immunoassay' named entity 'serology' named entity 'parainfluenza virus' named entity 'RSV' named entity 'nasopharyngeal' named entity 'virus' named entity 'immunoassay' named entity 'viruses' named entity 'RSV' named entity 'antigen' named entity 'infection' named entity 'virological' named entity 'RSV' named entity 'antigens' named entity 'nasopharyngeal' named entity 'antigen' named entity '1, 2' named entity 'mucus' named entity 'pneumonia' named entity 'adenovirus' named entity 'RSV' named entity 'IgG antibody' named entity 'virus' named entity 'virus isolation' named entity 'antigen' named entity 'serology' named entity 'antigen' named entity 'immunoassay' named entity 'microscale' named entity 'aetiological' named entity 'antibodies' named entity 'adenovirus' named entity 'viruses' named entity 'RSV' named entity 'serology' named entity 'virus' named entity 'parainfluenza' named entity 'antigen' named entity 'enzyme immunoassay' named entity 'Host factors' named entity 'respiratory infection' named entity 'virus' named entity 'virus' named entity 'respiratory syncytial virus' named entity 'lower respiratory tract infections' named entity 'pneumonia' named entity 'epidemic' named entity 'RSV' named entity 'pneumonia' named entity 'epidemiological' named entity 'host factors' named entity 'adenoviruses' named entity 'epidemic' named entity 'host factors' named entity 'mumps virus' named entity 'viruses' named entity 'lower respiratory tract infections' named entity 'coronaviruses'

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