About: Virome diversity analysis reveals novel enteroviruses and a human picobirnavirus in stool samples from African green monkeys with diarrhea

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About: Virome diversity analysis reveals novel enteroviruses and a human picobirnavirus in stool samples from African green monkeys with diarrhea Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Virome diversity analysis reveals novel enteroviruses and a human picobirnavirus in stool samples from African green monkeys with diarrhea
Creator	Bai, Bingke Fan, Hang Gao, Rong Hou, Jun Hu, Yan Huang, Yong Li, Wenjuan Mao, Panyong Mi, Zhiqiang Qiang, Xin Qin, Si Tong, Yigang Ye, Huahu Zhang, Xianglilan
Source	Elsevier; Medline; PMC
abstract	It is important to identify viruses in animals because most infectious diseases in humans are caused by viruses of zoonotic origin. African green monkey is a widely used non-human primate model in biomedical investigations. In this study, total RNAs were extracted from stool samples of 10 African green monkeys with diarrhea. High-throughput sequencing was used to characterize viromes. PCR and Sanger sequencing were used to determine the full genome sequences. Great viral diversity was observed. The dominant viruses were enteroviruses and picobirnaviruses. Six enterovirus genomes and a picobirnavirus RNA-dependent RNA polymerase sequence were characterized. Five enteroviruses belonged to two putative new genotypes of species Enterovirus J. One enterovirus belonged to EV-A92. The picobirnavirus RNA-dependent RNA polymerase sequence had the highest nucleotide similarity (93.48%) with human picobirnavirus isolate GPBV6C2. The present study helped to identify the potential zoonotic viruses in African green monkeys. Further investigations are required to elucidate their pathogenic roles in animals and humans.
has issue date	2020-03-10(xsd:dateTime)
bibo:doi	10.1016/j.meegid.2020.104279
bibo:pmid	32165243
has license	no-cc
sha1sum (hex)	ebc11164abf9d01ce97c28545b9627ab074dbced
schema:url	https://doi.org/10.1016/j.meegid.2020.104279
resource representing a document's title	Virome diversity analysis reveals novel enteroviruses and a human picobirnavirus in stool samples from African green monkeys with diarrhea
has PubMed Central identifier	PMC7102571
has PubMed identifier	32165243
schema:publication	Infect Genet Evol
resource representing a document's body	covid:ebc11164abf9d01ce97c28545b9627ab074dbced#body_text
is schema:about of	named entity 'Further' named entity 'caused' named entity 'picobirnavirus' named entity 'biomedical' named entity 'sequence' named entity 'human picobirnavirus' named entity 'Sanger sequencing' named entity 'enteroviruses' named entity 'GREAT' named entity 'INVESTIGATIONS' named entity 'HUMAN PICOBIRNAVIRUS' named entity 'VIRUSES' named entity 'DOMINANT' named entity 'HIGH-THROUGHPUT SEQUENCING' named entity 'STOOL' named entity 'Five' named entity 'genomes' named entity 'nucleotide' named entity 'One' named entity 'reveals' named entity 'diarrhea' named entity 'nucleotide' named entity 'enteroviruses' named entity 'diarrhea' named entity 'High-throughput sequencing' named entity 'infectious diseases' named entity 'picobirnavirus' named entity 'zoonotic' named entity 'viruses' named entity 'zoonotic origin' named entity 'African green monkeys' named entity 'viruses' named entity 'genomes' named entity 'Virome' named entity 'African green monkeys' named entity 'diarrhea' named entity 'African green monkeys' named entity 'picobirnavirus' named entity 'Viral' named entity 'ICTV' named entity 'genotypes' named entity 'African green monkeys' named entity 'Merck' named entity 'virus' named entity 'NCBI' named entity 'Caribbean' named entity 'TaKaRa' named entity 'non-human primate' named entity 'non-human primates' named entity 'enteroviruses' named entity 'high-throughput sequencing technology' named entity 'enterovirus' named entity 'viruses' named entity 'African green monkey' named entity 'viruses' named entity 'Roche' named entity 'FASTP' named entity 'phylogenetic tree' named entity 'African green monkeys' named entity 'metagenomic analysis' named entity 'Thermo Fisher Scientific' named entity 'picornavirus' named entity 'RNA-dependent RNA polymerase' named entity 'non-structural proteins' named entity '12,000' named entity 'nucleotide' named entity 'green monkeys' named entity 'virus'

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